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    What is Adapalene–Clindamycin used for?

    Adapalene–Clindamycin gel is a topical anti-acne medication indicated in the treatment of mild-to-moderate acne vulgaris (pimples). Adapalene–Clindamycin gel is a fixed-dose combination medicine composed of 2 drugs: 'Adapelene' (which belongs to a class of drugs called retinoid-like compounds) and 'Clindamycin'(which belongs to a class of drugs called antibiotics).

    Acne is caused when the overactive sebaceous glands increase the production of sebum (natural oil). This can result in clogged pores with dead skin cells, leading to an acne outbreak. Adapelene helps unclog pores, thereby reducing acne symptoms such as swelling and inflammation. Clindamycin works by stopping the growth of acne-causing bacteria.

    Adapalene–Clindamycin may also be used to treat other conditions as determined by your doctor.

    What is the recommended dosage of Adapalene–Clindamycin?

    The dosage of Adapalene–Clindamycin prescribed to each patient will vary. Always follow your physician's instructions and/or the directions on the prescription drug label.

    • Wash your hands before and after applying Adapalene–Clindamycin gel.
    • Before applying the gel, wash the affected area thoroughly and pat dry.
    • Apply a thin film of Adapalene–Clindamycin gel onto the affected area.

    What if you miss a dose of Adapalene–Clindamycin?

    If your physician has instructed or directed you to use Adapalene–Clindamycin medication in a regular schedule and you have missed a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and go back to your regular dosing schedule. Do not double the doses to catch up for the missed dose.

    What if you overdose on Adapalene–Clindamycin?

    Any medication used in excess can have serious consequences. If you suspect an overdose of Adapalene–Clindamycin, seek medical attention immediately.

    Overdose symptoms of Adapalene–Clindamycin may include

    • skin redness/peeling
    • watery/bloody diarrhea.

    What other drug(s) could interact with Adapalene–Clindamycin?

    It may be noted that drugs other than those listed above may also interact with Adapalene–Clindamycin. Make sure to inform your doctor if you are using any of the above-mentioned drugs.

    Adapalene–Clindamycin can interact with the following 'types' of medicines/products:
    -  topical medications (including other topical anti-acne medications);
    -  alcohol-containing skin medications;
    -  neuromuscular blocking agents;
    -  medicated/abrasive soaps;
    -  skin cleansers;
    -  astringents.

    Usually drug interactions may occur when certain drugs are used together. Before you consume a medication for a particular ailment, you should inform the health expert about the use of any prescription medications, over-the-counter products (non-prescription medications) and dietary supplements like vitamins, minerals and herbals, which may increase the effect of Adapalene–Clindamycin. This information can help your doctor to warn you of any possible drug interactions.

    Do let your doctor know if you smoke, consume alcohol or caffeinated drinks, or use illegal drugs as these may interfere with the action of your medication. It is also important to tell your healthcare professional if you have any medical conditions or a family history of any medical problems. Do not start or stop using any medicine without consulting your doctor.

    What are the side effects of Adapalene–Clindamycin?

    Like other medicines, Adapalene–Clindamycin can cause some side effects. If they do occur, the side effects of Adapalene–Clindamycin are most likely to be minor and temporary. However, some may be serious and may require the individual to inform the doctor or visit the nearest hospital immediately.

    It is pertinent to note that side effects of Adapalene–Clindamycin cannot be anticipated. If any side effects of Adapalene–Clindamycin develop or change in intensity, the doctor should be informed as soon as possible.

    Adapalene–Clindamycin can cause the following side effects:

    • temporary redness/dryness/burning/stinging/peeling/scaling/itching of skin at the site of application;
    • skin irritation or oily skin;

    This may not be a complete list of all side effects of Adapalene–Clindamycin. Do concur with your doctor and follow his directions completely when you are using Adapalene–Clindamycin.

    What are the questions to ask your doctor before using Adapalene–Clindamycin?

    Is it possible for me to use Adapalene–Clindamycin with other drugs?
    Should certain beverages, foods and other products be avoided when I use Adapalene–Clindamycin?
    What are the possible drug interactions of Adapalene–Clindamycin?
    How will Adapalene–Clindamycin work in my body?
    How should Adapalene–Clindamycin be used?
    How to reduce the risk of Adapalene–Clindamycin drug interactions and side effects?

    What other important information should you know about Adapalene–Clindamycin?

    Before using Adapalene–Clindamycin, make sure to tell your doctor if you

    • have any other skin problems (such as eczema);
    • have asthma;
    • have ulcerative colitis;
    • have or have had inflammatory bowel disease;
    • suffer from severe diarrhea due to antibiotics;
    • are pregnant, plan to become pregnant, or are breast-feeding.

    Also, let your doctor know if you are allergic to Adapalene–Clindamycin, or if you have ever had an allergic reaction to any other medicines.

    • Avoid getting the gel into your eyes, nose, mouth, vagina or rectum. In case of contact with eyes, rinse them immediately with plenty of water.
    • Topical Adapalene–Clindamycin gel is only for use on the skin. Do not swallow the medication.
    • Do not apply this gel to cuts, chapped, sunburned or broken skin.
    • The Adapalene–Clindamycin gel may make you more sensitive to the sun. Avoid direct exposure to sunlight, sunlamps and tanning beds. Wear protective clothing and use sunscreen if you must go out in the sun.
    • Avoid the use of chemical depilatories, waxing or electrolysis for removal of hair on the treated skin.


    The health and medical information provided here is intended to supplement and not substitute for the expertise and judgment of your physician, pharmacists or other health care professional. It should not be understood to indicate that the use of Adapalene–Clindamycin is safe, appropriate or effective for you. Always consult your health care professional before using this, or any other, drug.


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