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    You are here: Home > Pharmacy > E > Esomeprazole–Domperidone
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    What is Esomeprazole–Domperidone used for?

    Esomeprazole–Domperidone is a fixed dose combination medicine used in the treatment of gastroesophageal reflux disease (digestive disorder), Zollinger–Ellison syndrome (high acid levels in the stomach), dyspepsia (indigestion) and peptic ulcer disease (open sore in the lining of the stomach). Esomeprazole–Domperidone is also used to help prevent nausea and vomiting caused by certain medications (used for treating Parkinson's disease).

    Esomeprazole–Domperidone is a combination of 2 drugs: "Esomeprazole" and "Domperidone".

    Esomeprazole belongs to a group of drugs known as proton pump inhibitors. Esomeprazole works by reducing the amount of acid produced in the stomach, which helps relieve symptoms such as heartburn and difficulty swallowing.

    Domperidone belongs to a group of medicines called anti-emetics. By speeding up the movement of food through the digestive system, Domperidone helps treat nausea and vomiting.

    Esomeprazole–Domperidone may also be used to treat other conditions as determined by your doctor.

    What is the recommended dosage of Esomeprazole–Domperidone?

    The dosage of Esomeprazole–Domperidone may vary based on the patient's age, gender, body weight, medical condition and response to treatment. Always follow your physician's instructions and/or the directions on the prescription drug label.

    • Swallow Esomeprazole–Domperidone capsule with a full glass of water.

    What if you miss a dose of Esomeprazole–Domperidone?

    If your physician has instructed or directed you to take Esomeprazole–Domperidone medication in a regular schedule and you have missed a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and go back to your regular dosing schedule. Do not double the doses to catch up for the missed dose.

    What if you overdose on Esomeprazole–Domperidone?

    Any medication taken in excess can have serious consequences. If you suspect an overdose of Esomeprazole–Domperidone, seek medical attention immediately.

    Overdose symptoms of Esomeprazole–Domperidone may include

    • drowsiness
    • dizziness
    • irregular heartbeat
    • blurred vision
    • confusion
    • dry mouth
    • sweating
    • flushing

    What other drug(s) could interact with Esomeprazole–Domperidone?

    It may be noted that drugs other than those listed above may also interact with Esomeprazole–Domperidone. Make sure to inform your doctor if you are taking any of the above-mentioned drugs.

    Esomeprazole–Domperidone can interact with the following 'types' of medicines/products:
    - antiretroviral medications;
    - "azole" antifungals; 
    - anticoagulants;
    - HIV/AIDS medications;
    - macrolide antibiotics; 
    - monoamine oxidase inhibitors (MAOIs);
    - diuretics;
    - anticholinergics;
    - iron supplements;
    - grapefruit juice;
    - oral contraceptives.

    Usually drug interactions may occur when certain drugs are taken together. Before you take a medication for a particular ailment, you should inform the health expert about the intake of any prescription medications, over-the-counter products (non-prescription medications) and dietary supplements like vitamins, minerals and herbals, which may increase the effect of Esomeprazole–Domperidone. This information can help your doctor to warn you of any possible drug interactions.

    Do let your doctor know if you smoke, consume alcohol or caffeinated drinks, or use illegal drugs as these may interfere with the action of your medication. It is also important to tell your healthcare professional if you have any medical conditions or a family history of any medical problems. Do not start or stop using any medicine without consulting your doctor.

    What are the possible side effects of Esomeprazole–Domperidone?

    Like other medicines, Esomeprazole–Domperidone can cause some side effects. If they do occur, the side effects of Esomeprazole–Domperidone are most likely to be minor and temporary. However, some may be serious and may require the individual to inform the doctor or visit the nearest hospital immediately.

    It is pertinent to note that side effects of Esomeprazole–Domperidone cannot be anticipated. If any side effects of Esomeprazole–Domperidone develop or change in intensity, the doctor should be informed as soon as possible.

    Esomeprazole–Domperidone can cause the following side effects:

    • dry mouth
    • headache
    • dizziness
    • flushing
    • gas
    • diarrhea
    • constipation
    • abdominal pain
    • unusual production of breast milk
    • menstrual irregularities.
    • This may not be a complete list of all side effects of Esomeprazole–Domperidone. Do concur with your doctor and follow his directions completely when you are taking Esomeprazole–Domperidone.

      What are the questions to ask your doctor before taking Esomeprazole–Domperidone?

      Is it possible for me to take Esomeprazole–Domperidone with other drugs?
      Should certain beverages, foods and other products be avoided when I take Esomeprazole–Domperidone?
      What are the possible drug interactions of Esomeprazole–Domperidone?
      How will Esomeprazole–Domperidone work in my body?
      How should Esomeprazole–Domperidone be taken?
      How to reduce the risk of Esomeprazole–Domperidone drug interactions and side effects?

      What other important information should you know about Esomeprazole–Domperidone?

      Before taking Esomeprazole–Domperidone, make sure to tell your doctor if you

      • have liver disease;
      • suffer from osteoporosis;
      • have low levels of magnesium in blood;
      • are pregnant, plan to become pregnant, or are breast-feeding.
      • Esomeprazole–Domperidone may cause dizziness/drowsiness. Do not drive, operate machinery, or do any activities that require alertness until you are certain you can perform such tasks safely.
      • Also, let your doctor know if you are allergic to Esomeprazole–Domperidone, or if you have ever had an allergic reaction to any other medicines such as albendazole, dexlansoprazole, lansoprazole, mebendazole, omeprazole, pantoprazole and reprazole.


      The health and medical information provided here is intended to supplement and not substitute for the expertise and judgment of your physician, pharmacists or other health care professional. It should not be understood to indicate that the use of Esomeprazole–Domperidone is safe, appropriate or effective for you. Always consult your health care professional before using this, or any other, drug.


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