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    You are here: Home > Pharmacy > G > Glyburide/Glibenclamide-Metformin
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    What does Glyburide/Glibenclamide–Metformin treat?

    Glyburide/Glibenclamide–Metformin is an anti-diabetic medication that’s prescribed to manage blood sugar levels in patients with type 2 diabetes. This acts by promoting the body’s natural capacity to produce insulin. It helps to bring down levels of high sugar and prevent heart disease, nerve problems, kidney disease, strokes, impotence and blindness. Your physician may use this to treat other ailments based on their discretion.

    Dosage Instructions

    Follow the Glyburide/Glibenclamide–Metformin dosage prescribed by your physician. The dosage could vary based on individual patient requirements. Always follow your physician’s instructions or go by the directions on the prescription drug label. You can take it with meals.

    Missed a dose?

    Take it immediately once you remember. In case, this time falls close to the next dosage, skip it and get back to the prescribed schedule. Never take a double dose unless your physician specifically directs you to do so.


    Don’t waste any time and seek immediate medical attention.

    Drug Interactions

    Drug interactions must be considered before starting to take any kind of drug. Drug interactions might happen either when Glyburide/Glibenclamide–Metformin is taken along with another drug or with particular foods. To prevent any kind of negative interaction, make sure you inform your doctor of any drugs you are taking including non-prescription medication, OTCs, health supplements like vitamins, minerals, herbal medicine, drinks with caffeine and alcohol, illegal drugs, smoking habits and so on which may increase or interfere with the effect of Glyburide/Glibenclamide–Metformin.

    It may interact with: 

    • Furosemide 
    • Nifedipine 
    • Vancomycin 
    • Digoxin 

    It may also interact with steroids, thyroid medicines and diuretics. This is not an exhaustive list though.

    Appraise your doctor of any medical conditions that you are suffering from and your family history of medical ailments. It’s important that you do not stop or start taking any medicine without the consent of your physician.

    Possible Side Effects

    Glyburide/Glibenclamide–Metformin might have some side effects but it’s not possible to anticipate them. It does not have any major side effects and the minor ones that may occur are temporary. In rare cases, there might be major side effects and immediate medical attention must be sought.

    Some of the side effects could be sneezing, dizziness, mild nausea, vomiting, runny nose, headache, diarrhea and stomach pain. This is not the complete list though.

    In case, there is a change in intensity of side effects or if any new side effects develop, make sure you consult your doctor.

    What to ask your doctor before you start on Glyburide/Glibenclamide–Metformin

    • Can I take Glyburide/Glibenclamide–Metformin along with other drugs? 
    • Are there certain foods, beverages and products to be avoided while on Glyburide/Glibenclamide–Metformin? 
    • What is the dosage of Glyburide/Glibenclamide–Metformin to be consumed? 
    • How should I use Glyburide/Glibenclamide–Metformin? 
    • How will Glyburide/Glibenclamide–Metformin work on my body? 
    • How can the drug interactions and side effects of Glyburide/Glibenclamide–Metformin be minimized or completely avoided?


    The health and medical information that we have provided are meant to supplement and not substitute the advice of your physician, pharmacists or other health care professionals. This does not suggest that usage of Glyburide/Glibenclamide–Metformin is safe, appropriate or effective for you. Always ensure that you take this or any other drug only after consulting your physician.


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