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    You are here: Home > Pharmacy > P > Perindopril–Indapamide
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    What does Perindopril Indapamide treat?

    Perindopril Indapamide is a combination medication prescribed to treat high blood pressure which in turn helps cut down the risk of heart attack, stroke and kidney problems. Perindopril is an ACE inhibitor while Indapamide is a diuretic or water pill that helps to get rid of excess water and salt. The result is that the blood vessels relax and this helps prevent heart attack, stroke and kidney problems. Your physician may use this to treat other ailments based on their discretion.

    Dosage Instructions

    Follow the Perindopril Indapamide dosage prescribed by your physician. The dosage could vary based on individual patient requirements. Always follow your physician’s instructions or go by the directions on the prescription drug label. You must avoid direct exposure to sunlight. If you need to step out, use a sunscreen or wear protective clothing. You must not drive, operate machinery, or perform activities that need alertness while on this drug. Avoid getting pregnant while taking this and check with your doctor about using it if you are pregnant.

    Missed a dose?

    Take it immediately once you remember. In case, this time falls close to the next dosage, skip it and get back to the prescribed schedule. Never take a double dose unless your physician specifically directs you to do so.


    Don’t waste any time and seek immediate medical attention. Overdose symptoms that you may encounter include confusion, nausea, giddiness and low salt/potassium levels.

    Drug Interactions

    Drug interactions must be considered before starting to take any kind of drug. Drug interactions might happen either when Perindopril Indapamide is taken along with another drug or with particular foods. To prevent any kind of negative interaction, make sure you inform your doctor of any drugs you are taking including non-prescription medication, OTCs, health supplements like vitamins, minerals, herbal medicine, drinks with caffeine and alcohol, illegal drugs, smoking habits and so on which may increase or interfere with the effect of Perindopril Indapamide.

    It may interact with: 

    • Aspirin 
    • Ibuprofen 
    • Cyclosporine 
    • Naproxen 

    It may also interact with barbiturates, other high blood pressure medication, potassium-sparing diuretics, angiotensin II receptor antagonists, psychiatric medication, beta blockers, enzodiazepines, anti-arrhythmics, potassium-lowering drugs, non-steroidal anti-inflammatory drugs, immunosuppressants, diabetes medications and gold injections. This is not an exhaustive list though.

    Appraise your doctor of any medical conditions that you are suffering from and your family history of medical ailments. It’s important that you do not stop or start taking any medicine without the consent of your physician.

    Possible Side Effects

    Perindopril Indapamide might have some side effects but it’s not possible to anticipate them. It does not have any major side effects and the minor ones that may occur are temporary. In rare cases, there might be major side effects and immediate medical attention must be sought.

    Some of the side effects could be tiredness, headache, dizziness or lightheadedness. Serious side effects are rare but may include extreme thirst, dark urine, very dry mouth, muscle cramps/weakness, breathing problems, fast/slow/irregular heartbeat, swelling, confusion and decreased urination. This is not the complete list though.

    In case, there is a change in intensity of side effects or if any new side effects develop, make sure you consult your doctor.

    What to ask your doctor before you start on Perindopril Indapamide

    • Can I take Perindopril Indapamide along with other drugs? 
    • Are there certain foods, beverages and products to be avoided while on Perindopril Indapamide? 
    • What is the dosage of Perindopril Indapamide to be consumed? 
    • How should I use Perindopril Indapamide? 
    • How will Perindopril Indapamide work on my body? 
    • How can the drug interactions and side effects of Perindopril Indapamide be minimized or completely avoided?


    The health and medical information that we have provided are meant to supplement and not substitute the advice of your physician, pharmacists or other health care professionals. This does not suggest that usage of Perindopril Indapamide is safe, appropriate or effective for you. Always ensure that you take this or any other drug only after consulting your physician.


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