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    What is Sodium Valproate–Valproic Acid used for?

    Sodium Valproate–Valproic Acid is an anti-epileptic drug used to treat different types of epilepsy (including generalized and partial epilepsy) and seizures. Sodium Valproate–Valproic Acid has also been used as a mood stabilizer to treat acute manic episodes associated with bipolar disorder (manic-depressive disorder). Sodium Valproate–Valproic Acid may also be prescribed for the prevention of migraine headache.

    Sodium Valproate–Valproic Acid is a combination medication that contains 2 drugs: Sodium Valproate and Valproic Acid, both of which belong to a class of medications called anticonvulsants or anti-epileptic agents.

    Epilepsy is a condition characterized by sporadic electrical storms in the brain commonly known as seizures (fits). Sodium Valproate stabilizes the abnormal electrical activity in the brain, while Valproic Acid works by increasing the amount of a certain natural chemical in the brain. These actions of Sodium Valproate–Valproic Acid can help reduce the occurrence of seizures.

    Sodium Valproate–Valproic Acid may also be used to treat other conditions as determined by your doctor.

    What is the recommended dosage of Sodium Valproate–Valproic Acid?

    The dosage of Sodium Valproate–Valproic Acid may vary based on the patient’s age, sex, body weight, medical condition and response to treatment. Always follow your physician’s instructions and/or the directions on the prescription drug label.

    To avoid missing doses, take Sodium Valproate–Valproic Acid tablets at the same time each day.

    How should you take Sodium Valproate–Valproic Acid?

    Take Sodium Valproate–Valproic Acid tablets with a full glass of water, preferably after food.

    What if you miss a dose of Sodium Valproate–Valproic Acid?

    If your physician has instructed or directed you to take Sodium Valproate–Valproic Acid medication in a regular schedule and you have missed a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and go back to your regular dosing schedule. Do not double the doses to catch up for the missed dose.

    What if you overdose on Sodium Valproate–Valproic Acid?

    Any medication taken in excess can have serious consequences. If you suspect an overdose of Sodium Valproate–Valproic Acid, seek medical attention immediately.

    Overdose symptoms of Sodium Valproate–Valproic Acid may include

    • sleepiness
    • loss of consciousness
    • irregular heartbeat

    What other drug(s) could interact with Sodium Valproate–Valproic Acid?

    The following drugs may interact with Sodium Valproate–Valproic Acid:

    It may be noted that drugs other than those listed above may also interact with Sodium Valproate–Valproic Acid. Make sure to inform your doctor if you are taking any of the above-mentioned drugs.

    Sodium Valproate–Valproic Acid can interact with the following ‘types’ of medicines/products:

    • other anti-epileptic medicines
    • certain antibiotics
    • certain antidepressants
    • salicylates
    • anticoagulants
    • benzodiazepines
    • antiviral medicines
    • neuroleptic agents
    • sleep medicines
    • stomach medicines
    • cholesterol-lowering medicines
    • antimalarial medicines

    Usually drug interactions may occur when certain drugs are taken together. Before you take a medication for a particular ailment, you should inform the health expert about the intake of any prescription medications, over-the-counter products (non-prescription medications) and dietary supplements like vitamins, minerals and herbals, which may increase the effect of Sodium Valproate–Valproic Acid. This information can help your doctor to warn you of any possible drug interactions.

    Do let your doctor know if you smoke, consume alcohol or caffeinated drinks, or use illegal drugs as these may interfere with the action of your medication. It is also important to tell your healthcare professional if you have any medical conditions or a family history of any medical problems. Do not start or stop using any medicine without consulting your doctor.

    What are the possible side effects of Sodium Valproate–Valproic Acid?

    As with other medications, Sodium Valproate–Valproic Acid can cause some unwanted side effects, along with the desired therapeutic effect. If they do occur, the side effects of Sodium Valproate–Valproic Acid are most likely to be minor and temporary. However, some may be serious and may require the individual to inform the doctor or visit the nearest hospital immediately.

    It is pertinent to note that side effects of Sodium Valproate–Valproic Acid cannot be anticipated. It should also be noted that not everyone using Sodium Valproate–Valproic Acid will experience the side effects stated below. The occurrence of side effects may vary for each person depending on his/her age, sex, weight, dose, treatment duration, state of the disease, and overall health.

    Sodium Valproate–Valproic Acid can cause the following side effects:

    • nausea
    • vomiting
    • stomach pain
    • headache
    • diarrhea
    • constipation
    • weight gain
    • dizziness
    • drowsiness
    • transient hair loss
    • irregular menstrual periods
    • shakiness (tremor)
    • changes in appetite
    • ringing in the ears
    • behavioral changes

    This may not be a complete list of all side effects of Sodium Valproate–Valproic Acid. If any side effects of Sodium Valproate–Valproic Acid develop or change in intensity, inform your doctor as soon as possible. Do concur with your doctor and follow his directions completely when you are taking Sodium Valproate–Valproic Acid.

    What are the questions to ask your doctor before taking Sodium Valproate–Valproic Acid?

    • Will Sodium Valproate–Valproic Acid interact with other drugs I take?
    • Should certain beverages, foods and other products be avoided when I take Sodium    Valproate–Valproic Acid?
    • Are there any other drugs that would interact with Sodium Valproate–Valproic Acid?
    • What side effects can I expect from taking Sodium Valproate–Valproic Acid?
    • How to reduce the risk of Sodium Valproate–Valproic Acid drug interactions and side effects?
    • How often will I have to take Sodium Valproate–Valproic Acid?
    • For how long should I take Sodium Valproate–Valproic Acid?
    • When and how should Sodium Valproate–Valproic Acid be taken?
    • How will Sodium Valproate–Valproic Acid work in my body?

    What should you tell your doctor before using Sodium Valproate–Valproic Acid?

    Before taking Sodium Valproate–Valproic Acid, make sure to tell your doctor if you

    • have liver problems;
    • have kidney problems;
    • suffer from mental illness;
    • suffer from urea cycle disorders;
    • have systemic lupus erythematosus (also called lupus);
    • suffer from porphyria (a rare inherited blood disorder);
    • have bleeding problems;
    • suffer from Alpers–Huttenlocher syndrome;
    • have HIV infection;
    • have cytomegalovirus (CMV) infection;
    • plan to have surgery;
    • are pregnant, plan to become pregnant, or are breast-feeding.

    Also, let your doctor know if you are allergic to Sodium Valproate–Valproic Acid, or if you have ever had an allergic reaction to any other medicines.

    What other important information should you know about Sodium Valproate–Valproic Acid?

    • Sodium Valproate–Valproic Acid may cause dizziness/drowsiness. Do not drive, operate    machinery, or do any activities that require alertness until you are certain you can perform    such tasks safely.
    • Before having any laboratory tests, make sure to inform your doctor and the laboratory    personnel that you are taking Sodium Valproate–Valproic Acid.
    • Avoid alcoholic beverages while on treatment with Sodium Valproate–Valproic Acid.


    The health and medical information provided here is intended to supplement and not substitute for the expertise and judgment of your physician, pharmacists or other health care professional. It should not be understood to indicate that the use of Sodium Valproate–Valproic Acid is safe, appropriate or effective for you. Always consult your health care professional before using this, or any other, drug.


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