Amitriptyline is used to treat mental/mood disorders such as depression. It is in a class of medications called tricyclic antidepressants. This medicine relieves anxiety and tension, increases your energy level, and so on. It works by affecting the balance of certain natural chemicals such as serotonin in the brain. This medicine may also be used to treat other conditions as determined by your doctor.

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What does Amitriptyline treat?

This falls into a class of drugs known as tricyclic antidepressants. This is used in the treatment of mental/mood disorders such as depression. It works on restoring the balance of neurotransmitters such as serotonin in the brain. Balancing these chemicals in the brain elevates the sense of well-being, improves the mood, lifts depression, clears anxiety and tension, improves sleep and increases energy levels.

Possible Side Effects

Amitriptyline might have some side effects but it’s not possible to anticipate them. It does not have any major side effects and these are temporary. In rare cases there might be major side effects and immediate medical attention must be sought.

Side effects may include dry mouth, blurred vision, constipation, nausea, bruising, vomiting, tiredness, swelling, weight gain and headache. In very rare cases, there could be serious side effects such as irregular heartbeat, severe confusion, muscle spasms and persistent heartburn. This list however is not exhaustive. Always follow your physician’s instructions strictly.

Dosage Instructions

Follow the Amitriptyline dosage prescribed by your physician. The dosage could vary based on individual patient requirements. Always follow your physician’s instructions or go by the directions on the prescription drug label.


Missed a dose?

Take it immediately once you remember. In case, this time is closer to the next dosage, skip it and get back to the prescribed schedule. Never take a double dose unless specifically directed by your physician.


Don’t waste any time and seek immediate medical attention.

Drug Interactions

Drug interactions must be considered before starting to take any kind of drug. Drug interactions might happen either when Amitriptyline is taken along with another drug or with particular foods. To prevent any kind of negative interaction, make sure you inform your doctor of any drugs you are taking including non-prescription medication, OTCs, health supplements like vitamins, minerals, herbal medicine and so on which may increase the effect of Amitriptyline.

This drug may interact with:


  • Disulfiram


It may also interact with pain medications, heart rhythm medications and seizure medications. This is not an exhaustive list though.

Appraise your doctor of any medical conditions that you are suffering from and your family history of medical ailments. It’s important that you do not stop or start taking any medicine without the consent of your physician.

Is Amitriptyline good for migraine?

Amitriptyline medication influences the body’s use of serotonin and norepinephrine which helps in leading to improvement in depression and several types of chronic pain. This medication is used for the treatment of chronic tension-type headache as well as migraine headache. Amitriptyline alternative is available which works similar

Where can I buy Amitriptyline over the counter?

Amitriptyline over the counter medication is available on prescription only. It comes as tablets and as a liquid which can help you drink it away. Amitriptyline is also used to treat depression like condition. You can request a prescription for this medication as an online medical evaluation with a licensed doctor. If the doctor determines that you can benefit from amitriptyline medication, they shall electronically send the prescription to the pharmacy of your choice.

Can I buy Amitriptyline without a prescription?

Amitriptyline without prescription is not possible as this medication is an antidepressant solutio n. It’s used to treat low mood and depression like condition. This medicine is only available on prescription. It comes as tablets and as a liquid. You need a prescription because under US federal law it is a prescription-medicine. With Lemonaid Health you can order this prescription medication you need without having to see a doctor or nurse practitioner in person.


What to ask your doctor before you start on Amitriptyline


  • Can I take Amitriptyline along with other drugs? 
  • Are there certain foods, beverages and products to be avoided while on Amitriptyline? 
  • What is the dosage of Amitriptyline to be consumed? How should I use Amitriptyline? 
  • How will Amitriptyline work on my body?
  •  How can the drug interactions and side effects of Amitriptyline be minimized or completely avoided?



The health and medical information that we have provided are meant to supplement and not substitute the advice of your physician, pharmacists or other health care professionals. This does not suggest that usage of Amitriptyline is safe, appropriate or effective for you. Always ensure that you take this or any other drug only after consulting your physician.