amlodipine cause weight gain blog image

Calcium channel blockers are primarily used for the treatment of high blood pressure and certain types of chest pain called angina. Amlodipine belonging to this class of drugs is commonly prescribed for the above conditions and various other conditions. Certain medications that are commonly prescribed as part of treatment regimen for the above conditions, often end up causing weight gain. Following subsections offer a detailed look at the drug, including answers to the question – does amlodipine cause weight gain?

Conditions treated with amlodipine

The drug is typically prescribed for treating the following conditions:

Additionally, the drug is also prescribed off-label for other conditions, including Raynaud’s disease, heart failure, or certain arrhythmias. Amlodipine is typically used as part of a comprehensive treatment plan that includes lifestyle changes – dietary modifications, regular exercise, and smoking cessation, to effectively manage hypertension and angina.

Ideal dosage of amlodipine for different conditions

The ideal dosage of amlodipine varies depending on the condition being treated, individual patient factors, and the evaluation of the prescribing healthcare provider. Here are the typical dosage ranges for amlodipine for different conditions, though this does not substitute medical advice:

Hypertension (High Blood Pressure):

Chronic Stable Angina:

Vasospastic Angina:


Mechanism of action of amlodipine

Amlodipine works by blocking the influx of calcium ions into smooth muscle cells of the blood vessels and heart. This results in vasodilation and reduced contraction of the smooth muscle in the arterial walls. The mechanism of action of amlodipine can be summarized as follows:

By dilating blood vessels and reducing cardiac workload, amlodipine lowers blood pressure and improve blood flow to the heart, relieving symptoms of hypertension and angina.

Side effects of amlodipine

Amlodipine, like all medications, can cause side effects in some individuals. Not everyone is likely to experience side effects, and the severity and frequency can vary. Common side effects of amlodipine may include the following:

Does amlodipine cause weight gain?

Weight gain is not commonly reported as a side effect of amlodipine. On the contrary, amlodipine is generally considered to be weight-neutral, and does not typically cause significant changes in body weight. However, individual responses to medications can vary, and some people may experience weight changes while taking amlodipine, due to lifestyle, diet, underlying health conditions, and other medications taken concurrently.

How to prevent and deal with weight gain from amlodipine?

Simple methods can help prevent or manage weight gain from medications, including amlodipine when taken as part of a treatment regimen with other medications.

#1 Maintain a balanced and healthy diet: Consuming a well-balanced diet including a variety of fruits, vegetables, whole grains, lean proteins, and healthy fats. Avoid large portion sizes and excessive intake of high-calorie, processed, or sugary foods.

#2 Engage in regular physical activity: Regular exercise can help maintain a healthy weight and improve overall cardiovascular health. A minimum of 150 minutes of moderate-intensity aerobic exercise per week, along with strength training exercises will help maintain weight.

#3 Assess impact of medications and lifestyle factors: Some medications or lifestyle factors, such as certain antidepressants, antipsychotics, or a sedentary lifestyle, can contribute to weight gain.

#4 Seek evaluation and assistance from a healthcare provider: Individuals experiencing significant weight gain re to seek evaluation from healthcare providers, and consider alternative treatment options wherever necessary.

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