depigmenting iamge

Depigmenting is a treatment for the loss of pigment of your skin. Loss of skin pigment can either be complete or partial. Complete loss is due to a condition called vitiligo; here again, this can be either permanent (albinism) or temporary. On the other hand, partial loss of skin pigment occurs due to injuries on skin. Depigmentation aims to remove such skin conditions by the use of depigmenting agents. It is a good thing to more about perfect clean depigmenting in greater detail.

Due to a few autoimmune conditions like vitiligo your skin may lose its pigmentation. This loss manifests as a damage or loss of pigment-making cells (known as melanocytes) of the skin. As a result, your skin may appear bleached with light patches. It can be disabling to those who have darker skin. This is quite common among people living in India and in some regions of China. Genetic makeup – especially, family history of skin-based autoimmune conditions is largely attributed to its onset.

Perfect clean depigmenting

There are a few approaches used for the management of vitiligo. Your dermatologist/skin doctor may prescribe topical corticosteroids, derivatives of vitamin-D (of the topical genre), skin creams such as ruxolitinib, etc. Other approaches include use of prostaglandin inhibiting meds and pseudo-catalase; however, these usages are not evidenced in full.

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Topical corticosteroids to perfect clean depigmenting – These drugs work as anti-inflammatory agents as well as immunosuppressants. Potency of such drugs depend on the quantum that actually enters into the affected cells; efficacy also depends on extent of absorption of topical corticosteroids applied onto your skin. You can procure these meds either as gel or an ointment. In some cases, they may also be purchased as adhesive tapes.

Most widely used drugs in this genre are clobetasol propionate, betamethasone-dipropionate, hydrocortisone, etc. The aforesaid belong to the highly potent genre of topical corticosteroids used for treating depigmentation. There are a few milder versions of these drugs viz., hydrocortisone-acetate as well as hydrocortisone. These steroidal meds may trigger a few side effects; if you encounter adverse effects such as thinning down of skin, stretch-marks at sites of application, added thickness of hair, etc., you are advised to consult your skin doctor without any further delay.

Calcineurin inhibiting ointment/cream to perfect clean depigmenting

This includes creams like pimecrolimus as well as tacrolimus ointments. Of this, pimecrolimus is a steroid-less med that modulates your immune cells. It is also known to have anti-inflammatory capabilities. The latter in the above listing – i.e., tacrolimus – is a macrolide-calcineurin inhibiting agent known for its immunosuppressant properties.

Ruxolitinib cream to perfect clean depigmenting – This is used for the management of non-segmental forms of vitiligo. This cream is a janus-activated tyrosine-kinases inhibiting med i.e., JAK 1 as well as JAK 2. However, those who have prior spells of hypersensitivity or allergies to this cream (and its key ingredients) must tell your dermatologist of such conditions. Moreover, use of CYP3A4 inhibiting items – such as grapefruit and its juice, azole-based antifungal meds, etc. must be avoided.

The aforesaid approaches to perfect clean depigmenting may cause rashes on skin (in some users), and also gastric discomforts such as nausea, vomiting or indigestion. In such cases, it becomes essential to take medical assistance on an emergency basis. Users of these meds who live in US are advised to call 911; those who live in Canada must go to a poison control unit closer to where they reside. Measures for perfect clean depigmenting must not be taken through the over-the-counter (OTC) route. It is highly recommended to pursue treatment as per the advice and guidance of a qualified skin physician i.e., dermatologist.


Information provided here are only of supplementary nature. Information shared here does not substitute a qualified doctor’s advice. This website is not suggesting intake of this drug as safe or appropriate. Hence it is advised to talk to your doctor before consuming this med or any other drug.

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