Symptomatic treatment of various conditions commonly involve the use of medications for pain management. NSAIDs are preferred medications for pain management associated with certain conditions including menstrual cramps and arthritis among others. Typically, patients are known to experience headache, fever and muscular pain as a result of these conditions. The idea of prescribing or taking analgesics or other medications is to deal with the symptoms along with the underlying conditions. Advil, belonging to the category of NSAIDs, contains the active ingredient Ibuprofen and is used as OTC products and as prescription medication. Medications without exception come with the possibility of undesirable effects; lets understand all about the possible side effects of Advil and practical tips to deal with the side effects.

Why are opioids and steroids are not the best option always for pain management?

Opioids and steroids are known to be more potent, with relatively swift outcomes. However, these potent categories of medications come with increased risk of side effects and this renders the medications unsafe for use in most circumstances. Steroids and opioids are prescribed when the need for swift results is overriding in nature and undesirable outcomes are considered as a lesser problem comparatively. Advil, as a NSAID is an effective option along with other NSAIDs for pain management in a majority of conditions.

What properties make certain NSAIDs desirable?

Analgesic and anti-inflammatory properties combine to make NSAIDs with Ibuprofen as a desirable choice. The dual properties of Ibuprofen are not delivered in all strengths, but specific properties manifest depending on the actual dosage administered. Analgesic properties are delivered in lower dosages (typically OTC formulations) while anti-inflammatory properties are delivered when the dosage is high (prescription strengths). This dose dependent mechanism of action and properties make this a suitable choice to treat various conditions with greater flexibility.  Conditions that are well managed include fever, pain, and inflammation; and additionally, the medication comes with better tolerance and lesser side effect profile.

Compilation of conditions that can be effectively treated with NSAIDs

In addition to the conditions mentioned above, Advil and other NSAIDs of this category are effective for treating dental pain. The medication is also effective for managing migraine, arthritis, menstrual cramps, muscular pain apart from fever.  Available in different formulations, intended for specific conditions, Advil is effective when the right type of formulation is used. Thoughtful deigns include the easy open arthritis cap that is intended for patients with arthritis. The dispenser is easy to handle, making it convenient for individuals, without having to seek assistance for taking the medication.


What are the different condition specific formulations?

Advil is available in six condition specific formulations, namely tablets, liquid-gel minis, easy open arthritis cap, dual action, Advil liquid-gels, and migraine. As the names suggest, the medications in specific forms are more suitable in the management of certain conditions, offering convenience and desired outcomes. By virtue of containing Ibuprofen as the active ingredient, Advil is also available in strengths suitable for pediatric use, apart from being available as combination medications. Ibuprofen is a relatively common ingredient in multiple products that contain various ingredients for treating cold and allergy.

How does the formulation inhibit pain? 

Pain, fever, inflammation are linked to prostaglandins and thromboxane, belonging to the family of lipids. These lipids are responsible for the control of various processes, with prostaglandins typically forming at the site of tissue damage arising out injury, infection. The enzymes that are responsible for the synthesis of these lipids is COX, abbreviation for cyclooxygenase, typically categorized as COX-1 and COX-2.  Each of these categories of enzymes have specific roles to perform in triggering response to infections and injury. Medications for pain management typically involve a mechanism of action that inhibit either of the enzymes of both the enzymes. Medications that inhibit either of the enzymes are known as selective inhibitors of COX, while medications that inhibit both the enzymes are known as non-selective inhibitors. Advil belongs to the category of non-selective inhibitors, which effectively means that the medication has an extended action in pain, fever and inflammation management.

Are there possibilities of side effects of Advil?

Despite the tag of being well tolerated, with better side effects profile, there is the possibly of Advil causing unintended or undesirable outcomes. Prescription medications and OTC medications are all available commercially after stringent tests that assess the efficacy and the undesirable outcomes of medications. This includes the possibility of more numbers of control groups experiencing complications. Drugs are either not approved or come with severe warnings if the medications are known to cause adverse impact in a significant percentage of users participating in trials.

Undesirable effects of Advil may be experienced by certain categories of users, while some may not experience any effects whatsoever. The intensity of the effects or the duration of the effects may also be experienced differently by users. Mild effects are known to resolve naturally, while adverse effects may require some kind of medical attention depend on the actual condition. Allergies are a possible undesirable outcome of medications, and individuals are expected to treat allergies with sufficient levels of caution. Most individuals tend to assume that allergies constitute little or no risk; this is a wrong perception, as allergies can turn fatal at times. There is a need to identify the allergy outcome and extend suitable treatment on time, especially if it impacts the respiratory system.

What effects are mild in nature?

Mild effects, as outlined earlier are relatively common when compared with serious effects, that are typically rare in occurrence or limited to a specific section of users. The reason behind adverse outcomes could also be a particular health condition.  One of the most common types of undesirable effects includes feelings of flatulence or a full sensation in the stomach. This may at times, also be experienced along with diarrhea. On a contrasting note, a small section of users are known to suffer from constipation as a result of the adverse effects of the medication.

Nausea is another relatively common effect experienced by users, that may sometimes aggravate to vomiting. Dyspepsia, the symptom that refers to indigestion with upper abdominal pain is another undesirable effect that the medication may trigger. This symptom is even otherwise common to a little lesser than one third of the population, and the medication may trigger similar symptoms.

Any effects likely to be experienced by first time users?

First time users of the medication are likely to experience certain distinct effects. These effects may resolve without any intervention after the initial stages of taking the medication. Whenever, the medication is taken for a very short frequency, there is little cause for concern, as the effects will resolve naturally. However, when the medication is recommended to be taken on a long-term basis, patients may be apprehensive of the effects continuing. For instance, a nervous feeling is common among first time users.

Similarly, headaches are also commonly reported by first time users of the medication. These effects are not likely to last long and will resolve naturally. Mild outbreak of rashes is another commonly reported outcome, and may not require treatment. However, if the rashes do not resolve quickly, or of the rashes are intense, then it is necessary to seek medical intervention at the earliest. A ringing sensation in the ears is also likely to be experienced when on the medication. Known medically as tinnitus, this condition is limited to a small section of users.

Fluid retention or edema is a possibility, and this condition is not to be considered as mild. It can have long term consequences for users and therefore it is necessary to seek medical attention at the earliest. Symptoms that indicate fluid retention is swelling in the hands and feet, and if left untreated, can result in serious health complications that include damage to organs.

Which category of patients are to choose alternate options? 

Patients diagnosed with specific conditions are to avoid non-steroidal anti-inflammatory drugs. Liver complications, and patients with kidney problems are to pick alternate medications. Diuretics are also not to be taken with Ibuprofen. As diuretics have s more important desired outcome than Ibuprofen or NSAIDs, it is necessary to continue the diuretic and pick a different medication for pain, or fever management.

Patients already on some NSAIDs or medications contain Ibuprofen as an ingredient are to take a different medication, as the combination of multiple medications with Ibuprofen may result in accumulation, of the ingredient in the body, that may trigger undesirable outcomes. Patients are to carefully check medications, and bring to the attention of the treating specialist about the use of certain medications that contain Ibuprofen. Other medications that are not be taken alongside Ibuprofen include anticoagulants. All it takes to avoid undesirable outcomes, are simple preventive measures and complete care in understanding more about medications, at least from the contraindications point of view. This is especially important considering the large number of self-medication related events and the urge by patients to pop OTC formulations without much caution.

What kind of precautions are required to be followed?

Ibuprofen is considered as unsuitable for patients planning to undergo surgery. Similarly, patients who have undergone a surgery are also advised to strictly stay away from Ibuprofen medications. Patients who have undergone heart procedures, are to stop Advil and stick to alternate medications. The medication is also considered as unsafe for patients with chronic health conditions, such as stomach ulcers. Similarly, patients with a chronic case of heartburn or abdominal pain are also to avoid the medication. Internal bleeding in patients is linked to stomach ulcers and the mechanism of action of Ibuprofen may aggravate the condition and this could in turn end up as serious. It is therefore recommended that patients with a history of these conditions, avoid the medication.

Impact of Advil on routines and professional responsibilities

One of the side effects of Advil, as compiled above, includes dizzy feelings.  This could have a significant impact on professional responsibilities, especially roles that require alertness and quick reflexes. Machinery that are hazardous in nature, and driving responsibilities may turn into potentially risky situations, of the individual experiences dizziness. This could also extend to nausea, as the natural reflex action or gagging sensation may cause the individual to lose focus in the task being accomplished.

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