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What are the differences between Accutane and spironolactone

Accutane is widely used for treating acute spells of nodular (or, cystic) acne. This skin condition shows up in the form of reddened and painful breakouts in skin. This form of acne occurs when infections (caused by a few bacterial strands) get deeper. When cysts burst open, the underlying infections spreads-out quickly. You tend to experience itchiness as well as pains at infected areas. Hormonal imbalance – especially, androgen – is considered a primary reason. But what are the differences between Accutane and spironolactone? It is a good thing to know the differences.

Acne is a common condition that affects your skin; it often shows up when you attain the age of puberty. Those with greasy or oily skin are known to be more vulnerable. Hormonal imbalance – especially, male sex hormones – play a key role in the onset of cystic or nodular form of acne.

It is erroneously thought that inadequate hygiene or taking an unbalanced diet may work as triggers. However, extensive research done on acne do not include these as possible risks. Upon witnessing red spots / pimples on your face (or any other parts), it is a safe practice to talk to your dermatologist on a high priority mode.

What is Accutane?

This drug is essentially a version of vitamin A; this decreases the amount of oil your skin makes. This action helps your skin to get renewed. The chief use of this drug is to treat acute forms of cystic / nodular acne. This med is used when other drugs – say, antibiotics – fail to yield desired results.

Caveat: even a single dosage of this med may lead to serious birth-defects; in some instances, it has also led to the death of the fetus. Hence this drug is never used by women who are pregnant or those who have plans to get pregnant.

What is spironolactone?

Spironolactone is a diuretic; this med discharges excessive levels of liquids and salts from your body. This med makes you to urinate often and thus eliminates fluids along with bodily fluids. It is used for treating edema – due to kidney or liver problems, heart disorders, etc.

Key ingredients of spironolactone can control aldosterone; an essential hormone that regulates pressure as well as ensures proper circulation. Moreover, this hormone is associated with production of oil from glands present on skin. When openings that are home to hair-follicles are clogged with oil, it leads to conditions such as acne. Spironolactone is widely administered for treating this condition.

What are the differences between Accutane and spironolactone?

The main difference is spironolactone belongs to a class of meds called diuretics while Accutane is not a diuretic (it is an antineoplastic-retinoid). Owing to its ability to remove fluids and extra salts, spironolactone is used for treating edema, a few cardiac problems as well as deficiency of potassium (a condition called hypokalemia). On the other hand, Accutane is taken for treatment of rosacea, a few forms of non-lymphocytic leukemia, etc.

On the similarities front, both these meds are available as generic drugs; owing to this, you can procure them at a relatively lower cost. Both are available as orally administered pills / tablets. The half-life period of spironolactone is 37 hours while the half-life of Accutane hovers at ~ 33 hours. Accutane may cause serious damage to your fetus; hence its use during pregnancy is avoided. Though such acute damage of fetus may not occur while using spironolactone, marginal risks of fetal damage are not fully ruled-out.

If you encounter side effects like reddening of skin, rapid heartbeats (spells of arrhythmia), abdominal conditions like nausea / vomiting or a tingly sensation, you are advised to consult with your treating doctor without delay. Users living in the US are advised to call 911. Those living in any of the Canadian provinces need to reach out to Health Canada on an urgent mode.

Disclaimer

Information provided here are only of supplementary nature. Information shared here does not substitute a qualified doctor’s advice. This website is not suggesting intake of this drug as safe or appropriate. Hence it is advised to talk to your doctor before consuming this med or any other drug.