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Drug Information
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What does Carbidopa-Levodopa treat?

Carbidopa–Levodopa is a combination medication used to treat Parkinson’s disease or similar symptoms such as shakiness, stiffness and mobility issues. It helps to restore better muscle control and provide relief from tremors, muscle stiffness, shakiness, and spasms. These issues are linked to lack of adequate dopamine in the brain. Levodopa transforms into dopamine in the brain and this brings better control over movements. Carbidopa works to prevents the breakdown of Levodopa in the bloodstream allowing a greater quantity of it to enter the brain. Your physician may use this to treat other ailments based on their discretion.

Dosage Instructions

Follow the Carbidopa–Levodopa dosage prescribed by your physician. The dosage could vary based on individual patient requirements. Always follow your physician’s instructions or go by the directions on the prescription drug label. You may take it with or without food.

Missed a dose?

Take it immediately once you remember. In case, this time is closer to the next dosage, skip it and get back to the prescribed schedule. Never take a double dose.


Don’t waste any time and seek immediate medical attention.

Drug Interactions

Drug interactions must be considered before starting to take any kind of drug. Drug interactions might happen either when Carbidopa–Levodopa is taken along with another drug or with particular foods. To prevent any kind of negative interaction, Make sure you inform your doctor of any drugs you are taking including non-prescription medication, OTCs, health supplements like vitamins, minerals, herbal medicine and so on which may interfere with the effect of Carbidopa–Levodopa.

It may interact with: 

  • Amitriptyline 
  • Chlorpromazine
  • Doxepin 
  • Haloperidol 
  • Isoniazid
  • Metoclopramide
  • Nortriptyline 
  • Papaverine
  • Phenytoin 
  • Prochlorperazine
  •  Risperidone 

It may also interact with other Parkinson's medications, blood pressure medications and antidepressants. This is not an exhaustive list though.

Appraise your doctor of any medical conditions that you are suffering from and your family history of medical ailments. It’s important that you do not stop or start taking any medicine without the consent of your physician.

Possible Side Effects

Carbidopa–Levodopa might have some side effects but it’s not possible to anticipate them. It does not have any major side effects and the minor ones that may occur are temporary. In rare cases, there might be major side effects and immediate medical attention must be sought.

Side effects of Carbidopa–Levodopa that may develop include headaches, lack of appetite, cough, dry mouth, heartburn, diarrhea, nausea, chest pain, vomiting, constipation, insomnia, muscle pain dizziness, and blurred vision. Saliva, urine or sweat could turn darker in color. This is not an exhaustive list though. In case, there is a change in intensity of side effects or if any new side effects develop, make sure you consult your doctor.

What to ask your doctor before you start on Carbidopa–Levodopa

  • Can I take Carbidopa–Levodopa along with other drugs?
  •  Are there certain foods, beverages and products to be avoided while on Carbidopa–Levodopa? 
  • What is the dosage of Carbidopa–Levodopa to be consumed? 
  • How should I use Carbidopa–Levodopa? 
  • How will Carbidopa–Levodopa work on my body?
  •  How can the drug interactions and side effects of Carbidopa–Levodopa be minimized or completely avoided?


The health and medical information that we have provided are meant to supplement and not substitute the advice of your physician, pharmacists or other health care professionals. This does not suggest that usage of Carbidopa–Levodopa is safe, appropriate or effective for you. Always ensure that you take this or any other drug only after consulting your physician.


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