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Drug Information
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What does Clonidine treat?

Clonidine is a medication used in the treatment of high blood pressure or hypertension. Classified as a central alpha agonist, this works in the brain by relaxing blood vessels ensuring that blood flow is made easier. Lowering the blood pressure helps prevent other serious conditions such as strokes, heart attacks and kidney problems. It also treats attention deficit hyperactivity disorder, anxiety disorders, migraines, tic disorders and withdrawal symptoms from addictions. Your physician may use this to treat other ailments based on their discretion.

Possible Side Effects

Clonidine might have some side effects but it’s not possible to anticipate them. It does not have any major side effects and the minor ones that may occur are temporary. In rare cases, there might be major side effects and immediate medical attention must be sought.

Some of the side effects could be drowsiness, nausea, vomiting, fainting, irregular heartbeat, dry mouth, impotence, headache, rash, nervousness, breathing trouble and swelling. Rare side effects severe chest pain, shortness of breath, irregular heartbeats, very slow heart rate and severe headache. Besides these, there could be other side effects too.

In case, there is a change in intensity of side effects or if any new side effects develop, make sure you consult your doctor.

Dosage Instructions

Follow the Clonidine dosage prescribed by your physician. The dosage could vary based on individual patient requirements. Always follow your physician’s instructions or go by the directions on the prescription drug label. You may take it with or without food.

Missed a dose?

Take it immediately once you remember. In case, this time is closer to the next dosage, skip it and get back to the prescribed schedule. Never take a double dose unless your doctor specifically asks you to.


Don’t waste any time and seek immediate medical attention.

Drug Interactions

Drug interactions must be considered before starting to take any kind of drug. Drug interactions might happen either when Clonidine is taken along with another drug or with particular foods. To prevent any kind of negative interaction, make sure you inform your doctor of any drugs you are taking including non-prescription medication, OTCs, health supplements like vitamins, minerals, herbal medicine and so on which may interfere with the effect of Clonidine.

It may interact with:

  • Amitriptyline
  •  Amlodipine 
  • Atenolol
  •  Felodipine 
  • Verapamil

 It may also interact with classes of drugs such as antidepressants, calcium channel blockers and beta-blockers. This is not an exhaustive list though.

Appraise your doctor of any medical conditions that you are suffering from and your family history of medical ailments. Do let your doctor know if you are pregnant, planning to get pregnant or breast-feeding. It’s important that you do not stop or start taking any medicine without the consent of your physician.

Where can I buy Clonidine over the counter in the USA?

Clonidine medicine needs a prescription in the United States before one can get clonidine Over The Counter tablets at a pharmacy. At this time, one cannot buy clonidine online before consulting a licensed medical provider and clonidine over the counter is not available, either. Clonidine without prescription is not available. It is available as a patch, an oral tablet, and an oral extended-release tablet. The form you use shall all depend on the condition of your health.

Can I buy Clonidine without a prescription?

Clonidine Over The Counter medication is a fairly safe medication, but because of its effects and potential interactions, it is only available with a prescription. Clonidine Without Prescription is not available. Following a thorough consultation with a doctor and assessment of the reason is needed.

If you think you might further be benefitted from a Clonidine Over The Counter, you can book an online consultation with one of the doctors, for a consultation online or over the phone. This service also allows an individual to receive professional medical advice from the comfort of your own home.

What to ask your doctor before you start on Clonidine

  • Can I take Clonidine along with other drugs?
  • Are there certain foods, beverages and products to be avoided while on Clonidine? 
  • What is the dosage of Clonidine to be consumed?
  • How should I use Clonidine? 
  • How will Clonidine work on my body?
  • How can the drug interactions and side effects of Clonidine be minimized or completely avoided?


The health and medical information that we have provided are meant to supplement and not substitute the advice of your physician, pharmacists or other health care professionals. This does not suggest that usage of Clonidine is safe, appropriate or effective for you. Always ensure that you take this or any other drug only after consulting your physician.


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