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What is Clozapine used for?

Clozapine is an antipsychotic medication used to treat psychotic disorders such as severe schizophrenia. This drug is prescribed to people who have not responded to other antipsychotic medications. Clozapine is also used to reduce the risk of recurrent suicidal behavior in people with schizophrenia. This medicine belongs to a class of drugs known as atypical antipsychotics. It works by changing the actions of certain natural substances (neurotransmitters) in the brain. This medicine may also be used to treat other conditions as determined by your doctor.

What is the recommended dosage of Clozapine?

The dosage of Clozapine prescribed to each patient will vary. Always follow your physician’s instructions and/or the directions on the prescription drug label.

Clozapine can be taken with or without food.

What if you miss a dose of Clozapine?

If your physician has instructed or directed you to take Clozapine medication in a regular schedule and you have missed a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and go back to your regular dosing schedule. Do not double the doses unless otherwise directed.

What if you overdose on Clozapine?

Any medication taken in excess can have serious consequences. If you suspect an overdose of Clozapine, seek medical attention immediately.

What other drugs could interact with Clozapine?

It may be noted that drugs other than those listed above may also interact with Clozapine.

Usually drug interactions occur when it is taken with another drug or with food. Before you take a medication for a particular ailment, you should inform the health expert about intake of any other medications including non-prescription medications, over-the-counter medicines that may increase the effect of Clozapine, and dietary supplements like vitamins, minerals and herbal, so that the doctor can warn you of any possible drug interactions.

Clozapine can interact with heart rhythm medications and seizure medicines.

Do let your doctor know if you smoke, consume alcohol or caffeinated drinks, or use illegal drugs as these may interfere with the action of your medication. Make sure to inform your doctor of any medical conditions you may have, or any family history of medical problems. Do not start or stop using any medicine without consulting your doctor.

What are the side effects of Clozapine?

Like other medicines, Clozapine can cause some side effects. If they do occur, the side effects of Clozapine are most likely to be minor and temporary. However, some may be serious and may require the individual to inform the doctor or visit the nearest hospital immediately.

It is pertinent to note that side effects of Clozapine cannot be anticipated. If any side effects of Clozapine develop or change in intensity, the doctor should be informed as soon as possible.

Clozapine can cause side effects such as constipation, drowsiness, dizziness, headache, vision problems, and weight gain. This is not a complete list of all side effects. Do concur with your doctor and follow his directions completely when you are taking Clozapine.

What are the questions to ask your doctor before taking Clozapine?

Is it possible for me to take Clozapine with other drugs?
Should certain beverages, foods and other products be avoided when I take Clozapine?
What are the possible drug interactions of Clozapine?
How will Clozapine work in my body?
How should Clozapine be taken?
How to reduce the risk of Clozapine drug interactions and side effects?


The health and medical information provided here is intended to supplement and not substitute for the expertise and judgment of your physician, pharmacists or other health care professional. It should not be understood to indicate that the use of Clozapine is safe, appropriate or effective for you. Always consult your health care professional before using this, or any other, drug.


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