Disulfiram is an alcohol antagonist drug used to treat chronic alcoholism. This medication works by interfering with the processing of alcohol in the body. This medicine may also be used to treat other conditions as determined by your doctor.

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What does Disulfiram treat?

Disulfiram is a medication prescribed to treat chronic alcoholism. This belongs to the class of alcohol antagonists. It works by blocking the processing of alcohol by the body. Your physician may use this to treat other ailments based on their discretion.

Possible Side Effects

Disulfiram might have some side effects but it’s not possible to anticipate them. It does not have any major side effects and the minor ones that may occur are temporary. In rare cases, there might be major side effects and immediate medical attention must be sought.

Some of the side effects could be headache, garlic-like aftertaste, tiredness, drowsiness and acne. This is not the complete list though.

In case, there is a change in intensity of side effects or if any new side effects develop, make sure you consult your doctor.

Dosage Instructions

Follow the Disulfiram dosage prescribed by your physician. The dosage could vary based on individual patient requirements. Always follow your physician’s instructions or go by the directions on the prescription drug label. You can take it with or without food.


Missed a dose?

Take it immediately once you remember. In case, this time falls close to the next dosage, skip it and get back to the prescribed schedule. Never take a double dose unless your physician specifically directs you to do so.


Don’t waste any time and seek immediate medical attention.

Drug Interactions

Drug interactions must be considered before starting to take any kind of drug. Drug interactions might happen either when Disulfiram is taken along with another drug or with particular foods. To prevent any kind of negative interaction, make sure you inform your doctor of any drugs you are taking including non-prescription medication, OTCs, health supplements like vitamins, minerals, herbal medicine, drinks with caffeine and alcohol, illegal drugs, smoking habits and so on which may increase or interfere with the effect of Disulfiram.

It may interact with:


  • Amitriptyline
  • Metronidazole
  • Warfarin
  • Isoniazid


It may also interact with tricyclic antidepressants and monoamine oxidase inhibitors. This is not an exhaustive list though.

Appraise your doctor of any medical conditions that you are suffering from and your family history of medical ailments. It’s important that you do not stop or start taking any medicine without the consent of your physician.

What to ask your doctor before you start on Disulfiram


  • Can I take Disulfiram along with other drugs? 
  • Are there certain foods, beverages and products to be avoided while on Disulfiram? 
  • What is the dosage of Disulfiram to be consumed? 
  • How should I use Disulfiram? 
  • How will Disulfiram work on my body? 
  • How can the drug interactions and side effects of Disulfiram be minimized or completely avoided?



The health and medical information that we have provided are meant to supplement and not substitute the advice of your physician, pharmacists or other health care professionals. This does not suggest that usage of Disulfiram is safe appropriate or effective for you. Always ensure that you take this or any other drug only after consulting your physician.