Doxepin is used in the treatment of depression and anxiety. It belongs to a class of medications called tricyclic antidepressants. Doxepin is also used to treat depression due to alcoholism and bipolar disorder. This medication works by affecting the balance of certain natural substances in the brain. This medicine may also be used to treat other conditions as determined by your doctor.

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What does Doxepin treat?

Doxepin is a tricyclic-antidepressant medication indicated for treating mental problems such as depression especially due to alcoholism and bi-polar disorder. It restores the balance of your brain chemicals and relieves depression and anxiety. It will also improve the sense of well-being. This apart, your physician might use it to treat other medical conditions too.

Dosage Instructions

Follow the Doxepin dosage prescribed by your physician. The dosage could vary based on individual patient requirements. Always follow your physician’s instructions or go by the directions on the prescription drug label.

Missed a dose?

Take it immediately once you remember. In case, this time is closer to the next dosage, skip it and get back to the prescribed schedule. Never take a double dose unless specifically instructed by your doctor.


Don’t waste any time and seek immediate medical attention.

Drug Interactions

Drug interactions must be considered before starting to take any kind of drug. Drug interactions might happen either when Doxepin is taken along with another drug or with particular foods. To prevent any kind of negative interaction, make sure you inform your doctor of any drugs you are taking including non-prescription medication, OTCs, health supplements like vitamins, minerals, herbal medicine and so on which may interfere with the effect of Doxepin.

It may interact with:

  • Albuterol/Salbutamol
  • Ebastine-Phenylephrine
  • Sibutramine

It may also interact with medication such as thyroid supplements, bronchodilators, anticholinergic drugs, and MAO inhibitors. This is not an exhaustive list though.

Appraise your doctor of any medical conditions that you are suffering from and your family history of medical ailments. It’s important that you do not stop or start taking any medicine without the consent of your physician.

Possible Side Effects

Doxepin might have some side effects but it’s not possible to anticipate them. It does not have any major side effects and the minor ones that may occur are temporary. In rare cases, there might be major side effects and immediate medical attention must be sought.

Some of the side effects are drowsiness, dizziness, light-headedness, dry mouth, vision problems, constipation, and urinary retention. This is not the complete list though.

In case there is a change in intensity of side effects or if any new side effects develop make sure you consult your doctor.

What to ask your doctor before you start on Doxepin

  • Can I take Doxepin along with other drugs?
  • Are there certain foods, beverages and products to be avoided while on Doxepin?
  • What is the dosage of Doxepin to be consumed?
  • How should I use Doxepin?
  • How will Doxepin work in my body?
  • How can the drug interactions and side effects of Doxepin be minimized or completely avoided?

Where can I buy Doxepin over the counter?

Doxepin over the counter medication is a prescription-only medication, which means that you will all need to speak to a healthcare professional and receive a prescription before one might purchase Doxepin without prescription.

Can I buy Doxepin without a prescription?

Doxepin without prescription medication is a tricyclic antidepressant (TCA). This medication works well on the central nervous system (CNS) to enhance the levels of certain chemicals in the brain. This medicine is available only with the doctor’s prescription.


The health and medical information that we have provided are meant to supplement and not substitute the advice of your physician, pharmacists or other health care professionals. This does not suggest that usage of Doxepin is safe appropriate or effective for you. Always ensure that you take this or any other drug only after consulting your physician.