Losartan vs Metoprolol

LosartanMetoprolol
Angiotensin II receptor blocker (ARB)

Classification

Beta-blocker
Hypertension, Diabetic nephropathy

Indications

Hypertension, Angina, Heart failure, Heart attack
Blocks angiotensin II receptors, reducing vasoconstriction and aldosterone secretion

Mechanism of Action

Blocks beta-adrenergic receptors in the heart, reducing heart rate and cardiac output
Dizziness, Upper respiratory infections, Nasal congestion, Back pain

Common Side Effects

Fatigue, Dizziness, Depression, Shortness of breath, Bradycardia
Angioedema, Kidney failure, Hyperkalemia

Serious Side Effects

Heart block, Severe bradycardia, Heart failure exacerbation, Hypotension
Hypersensitivity to losartan, Pregnancy

Contraindications

Severe bradycardia, Heart block, Cardiogenic shock, Severe asthma
25-100 mg daily in 1 or 2 divided doses

Typical Dosage

25-100 mg daily in 1 or 2 divided doses
Potassium supplements, NSAIDs, Lithium

Drug Interactions

Other beta-blockers, Calcium channel blockers, Antidepressants
May be preferred in patients with diabetes for kidney protection

Considerations

Preferred in patients with prior heart attack or chronic heart failure
Generally lower cost than metoprolol

Cost without insurance

Generally higher cost compared to losartan

Coupon code

CMP30

Coupon code

Coupon code

CMP30

FAQ

What is the main difference between Losartan and Metoprolol?

Losartan is an angiotensin II receptor blocker (ARB), while Metoprolol is a beta-blocker. Losartan lowers blood pressure by relaxing blood vessels, whereas Metoprolol reduces heart rate and workload on the heart.

Can I take Losartan and Metoprolol together?

Yes, they are often prescribed together to manage high blood pressure or heart conditions. However, your doctor will monitor you closely for side effects like low blood pressure or dizziness.

Which is better for high blood pressure, Losartan or Metoprolol?

Both can be effective, but the best choice depends on your overall health. Losartan may be preferred for patients with kidney issues, while Metoprolol might be chosen for those with certain heart conditions.

Do Losartan and Metoprolol have different side effects?

Yes. Losartan may cause dizziness or high potassium levels. Metoprolol can lead to fatigue, slow heart rate, or cold extremities. Side effects vary per individual.

Are there any conditions where one is preferred over the other?

Yes. Losartan is often used in people with diabetes or kidney disease. Metoprolol is preferred for heart rhythm issues or after a heart attack. Always follow your doctor’s recommendation.