Neurontin vs Gabapentin
NeurontinGabapentin
AnticonvulsantDrug ClassAnticonvulsant
- Epilepsy (partial seizures) - Nerve pain (postherpetic neuralgia)Uses- Epilepsy (partial seizures) - Nerve pain (postherpetic neuralgia)
Binds to voltage-gated calcium channels to reduce excitatory neurotransmitter release.Mechanism of ActionSame as Neurontin.
- Capsules - Tablets - Oral solutionDosage Forms- Capsules - Tablets - Oral solution
- Seizures: 300 mg three times daily (adjustable) - Nerve pain: 900–1800 mg/day divided into 3 dosesTypical DosageSame as Neurontin (dosages may vary slightly by manufacturer)
- Dizziness - Fatigue - Weight gain - Blurred vision - Dry mouthSide EffectsSame as Neurontin.
- Antacids (e.g., aluminum hydroxide reduces absorption) - Alcohol increases dizziness and sedation.Drug InteractionsSame as Neurontin.
Higher due to being a brand-name drug.CostSignificantly lower as it is a generic version.
Clinically equivalent to Gabapentin.EfficacySame as Neurontin.
Dose-dependent absorption; lower at higher doses.BioavailabilitySame as Neurontin.
C (risk cannot be ruled out)Pregnancy CategoryC (risk cannot be ruled out)
NoControlled SubstanceNo
Limited data; may pass into breast milk.Lactation SafetyLimited data; may pass into breast milk.
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