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Tadalafil versus vardenafil which is better

Male impotence or erectile dysfunction is a medical condition. This leads to penile problems such as – inability to sustain an erection. This is fast turning into a common disorder among males. Earlier, this was thought to afflict men who are old; but, as wider research data emerge, it is evident that men of all age groups may get it. Meds such as tadalafil, vardenafil, etc. are prescribed to treat male impotence. Do you know tadalafil versus vardenafil which is better? It is beneficial to have added inputs on this front.

Impotence among males is one of the topics that has gained attention during the last few years. Men are aware that timely treatment is required to ensure a smooth relationship with partner(s).Leading causes for its occurrence include incidence of diabetes, being obese, aging, high levels of cholesterol in your bloodstream, etc. In some cases, excessive use of tobacco products, being depressed most of the time and onset of cardiac ailments have also contributed to erectile dysfunction.

Caregivers administer comprehensive treatment plans to manage impotence among males. They gather inputs about likely causes, current habits as well as presence of stressful factors, if any. Drugs are available to treat this sexual condition.

Most widely used meds belong to a genre called PDE – 5 inhibiting drugs. PDE – 5 is an acronym of phosphodiesterase type – 5. One of the main functions of such drugs is to dilate your blood vessels; as a result, blood supply to your penis improves. These actions result in sustaining penile erection when you engage in an intercourse.

In this light, what is tadalafil?

This drug is prescribed for treating erectile dysfunction among males. As an extended use, it is taken for managing high blood pressure and for case management of benign prostatic hyperplasia. The effects of this drug – when taken for treating male impotence – kick-in in about 40 minutes’ times. The outcomes are seen to last for more than 30 hours from the time of each dose.

So, what is vardenafil?

This drug is also a PDE 5 inhibiting med. This is a popular medication for erectile dysfunction in men. This is usually taken orally. In terms of remedial outcomes, this med comes closer to sildenafil. As an added use, vardenafil is also administered for managing premature mode of ejaculation.

Tadalafil versus vardenafil which is better

Both these meds are PDE 5 inhibitors. Chemical structure of tadalafil is different from vardenafil’s. Also, vardenafil has a shorter response time than tadalafil; but the time it takes is longer than that of sildenafil. Another salient difference is vardenafil has no effect on substances like PDE 6; you are hence unlikely to develop vision-related effects.

Tadalafil is available as an oral pill. Vardenafil is sold as a disintegrating tablet and as a pill. Both these meds are available as generic offerings. So, you can make savings on purchase of their generic equivalents.

Tadalafil-versus-vardenafil-which-is-better in a webo image

Another difference is the time taken to reduce traces of drugs to half. This is called half-life period. Tadalafil has a half-life of 17.5 hours while vardenafil halves itself in 5 hours.

Both drugs are known to lower your blood pressure level. It is recommended not to take them with alcohol. Beware of taking grapefruit as it can enhance the presence of vardenafil in blood.

Not stopping with this, you are advised to tell your doctor of your other medication plans. If you are taking any nitrate-based drugs, it is a vital thing to share details of such drugs with your caregiver. In general, make a list of all meds and dietary supplements you are presently taking.

Last but not least, talk to your treating physician about tadalafil versus vardenafil which is better; having more details can help stay aware of the side effects and to enhance the efficacy of these meds.

Disclaimer

Information provided here are only of supplementary nature. Information shared here does not substitute a qualified doctor’s advice. This website is not suggesting intake of this drug as safe or appropriate. Hence it is advised to talk to your doctor before consuming this med or any other drug.

Trazodone maximum dose for sleep

Antidepressants can manage mental conditions like depression. Spells of depression need to be treated without delay. Those who leave them untreated may witness an impairment of overall wellbeing. Your appetite may drop and your energy level may hit a low; all these in turn lead you into a state of malaise. Upon feeling down or depressed for more than 3 – 4 days, it is advised to consult a mental healthcare provider. Your caregiver is likely to prescribe antidepressants like trazodone. Do you know trazodone maximum dose for sleep? It is useful to have more details.

Mood-related conditions like depression push you to episodes of hopelessness and / or sadness. The worse thing is these episodes may last for long. Gradually, these conditions may adversely impact your daily way of living. You may not enjoy doing the activities you like doing. Your relationships with others may also suffer owing to such mood shifts.

Risks of being depressed tend to be more when your experience unpleasant events like death of a family member, going through a divorce or being unemployed. Family history of mental conditions is also another risk factor. If you are habituated to use of alcohol or addictive drugs, possibilities of depression increase.

In this light, what is trazodone?

This is an antidepressant categorized under serotonin receptor agonist and reuptake inhibitor (SARI). You need to know that this med has similarities with selective serotonin reuptake inhibitors (SSRIs); however, this is not grouped under SSRIs. This drug is chiefly used for major depressive disorders.

Caution: trazodone must not be taken along with MAO inhibiting meds such as linezolid, isocarboxazid, phenelzine, etc. It is a vital thing to provide an interval of at least 2 weeks’ time after stopping the doses of MAO inhibitors like tranylcypromine, etc. Moreover, if you witness mood shifts or anxieties, sleeping problems (such as insomnia), etc., inform your doctor of all such discomforts. This medication is not offered to younger adults – especially, people aged below 18 years.

Trazodone maximum dose for sleep

As an extended use, trazodone is used for treating conditions like insomnia. This med does not form habits. Also, it is known to offer added advantages as compared to other sleep-aids used to treat sleep-related conditions like sleep apnea.

The typical dosage of trazodone for sleep ranges from 25 milligrams (mg) to 100 mg. Doctors however prescribe lesser dosage strength; lower strength causes lesser levels of sleepiness during daytime. Lower dosages also ensure less-acute side effects since it is a short-acting drug.

Dosages of lesser strength treat primary and secondary insomnia. Primary form of sleeplessness is not caused by any other reason. Risks include living under stress, working in shifts, travels, etc. Secondary insomnia can show up due to intake of caffeine, alcohol or tobacco, a few drugs, etc.

If you drink alcohol along with trazodone, a normal dosage of 20 mg can become an overdose. Also, co-administration of benzodiazepines and / or CNS-depressants can make normal doses to turn into an overdose. You tend to have breathing difficulties such as panting for breath, wheezing or gasping. Upon sensing any of these undesired side effects, you are advised to seek medical help on an emergency mode.

Trazodone-maximum-dose-for-sleep in a webp image

Safety aspects for trazodone dosage

If you are diagnosed with depression and sleeplessness, maximum dose is 400 mg. But this must not be mistaken as trazodone maximum dose for sleep. The best thing to do is to follow the guidelines of your treating doctor, and adhere to the medication plan prescribed to you.

Trazodone is not an over the counter (OTC) med. It can lead to near-fatal effects if you take a larger dose without being guided by a qualified caregiving professional. Lastly, you can obtain more details about trazodone maximum dose for sleep from your physician before commencing your treatment plan.

Disclaimer

Information provided here are only of supplementary nature. Information shared here does not substitute a qualified doctor’s advice. This website is not suggesting intake of this drug as safe or appropriate. Hence it is advised to talk to your doctor before consuming this med or any other drug.

What is pimecrolimus cream used for?

Immunosuppressant medications are known to prevent or inhibit the activities of your immunity cells. There are many sub-genres in this category; one of these sub-genres is known as calcineurin inhibitors. Of the many therapeutic uses, calcineurin inhibiting meds can treat skin conditions like atopic dermatitis (also called eczema) and a few other such conditions. Atopic eczema or simply, eczema is a chronic swelling of skin. You skin may crack and turn red. In this milieu, it becomes necessary to know about pimecrolimus, and what is pimecrolimus cream used for.

Skin conditions like atopic dermatitis or eczema are known to occur in some 19% of individuals at any point in time. Children and younger adults are more vulnerable to atopic eczema. Risks factors are many – such as problems with immunity cells, genetic factors, disorders relating to permeability of skin, etc. People residing in dry weather conditions are more vulnerable.

Treatment of atopic dermatitis involves the use of topical creams. In some cases, steroids such as corticosteroids are applied to protect your skin from flaring up. Your dermatologist (skin doctor) is also likely to prescribe moisturising cream to keep your skin less-dry; such measures keep atopic eczema under control. If any of these measures do not give needful relief, calcineurin inhibiting creams such as pimecrolimus are used.

So, what is pimecrolimus?

This is a drug used for treating eczema. This is strictly for topical use, and not to be used otherwise. If you have accidentally used this cream on your eyes or mouth, rinse those parts with water as quickly as you possibly can. Also, this med must not be used on open sores or cuts.  It is advised to store this cream at room temperature. Never keep it in your toilets as the moisture there can make this cream ineffective.

What is pimecrolimus cream used for?

This topical cream is chiefly used for treating eczema or atopic dermatitis. Pimecrolimus is prescribed if other meds for eczema have failed to treat your skin condition. It is also applied when you are not advised to use steroidal drugs. Key ingredients of pimecrolimus are known to alter your skin’s immunity cells; thus, this med reduces the adverse reactions eczema causes on skin.

This cream is never used among those who underwent a recent transplant procedure or in general, people with a weak immunity system. Some dermatologists use this cream for treating acne. But, in some users, it may cause adverse effects like inflammation or darkening of applied spots. Use of an apt antimicrobial cream becomes necessary in such cases. It is hence a wise thing to talk to your doctor about – can pimecrolimus cream be used for acne.

-is-pimecrolimus-cream-used-for in a webp image

Precautions needed before using pimecrolimus

Before using pimecrolimus, inform your doctor if you have prior allergies or hypersensitivity to immunosuppressants. Those with cancers on skin or topical infections like herpes or chicken pox must keep their caregiver updated of such conditions. Pimecrolimus is not safe on children – especially, those aged less than 2 years.

It is important to keep away from sun lamps, tanning booths or being directly exposed to sun’s rays. If you are going to go out after applying pimecrolimus, use protective garments like gloves, headgear, etc. As the odds of getting an infection stay high, keep away from those who have a viral infection viz., cold, flu, etc.

It is a key thing to apply this med as per the dosage plan of your caregiver. It is a good practice to read the instruction booklet carefully. It is highly recommended to wash your fingers with cleaning agents before as well as after using this cream.

Lastly, if you want to know more about can pimecrolimus cream be used on the face, talk to a qualified skin doctor before using this immunosuppressant cream.

Disclaimer

Information provided here are only of supplementary nature. Information shared here does not substitute a qualified doctor’s advice. This website is not suggesting intake of this drug as safe or appropriate. Hence it is advised to talk to your doctor before consuming this med or any other drug.

Pentoxifylline side effects

Peripheral artery-based disorder or disease (in short, PAD) shows up when your blood vessels shrink. However, this condition does not involve constriction of arteries that supply blood to your cerebral system or cardiac system. This disease may instead occur in any other blood vessels; often, these may show up in your limbs – especially, legs. You need to know that this is different from peripheral veinous disorder; here, veins carrying blood back to heart are blocked. Pentoxifylline is a widely used medication for treating PAD. But what are pentoxifylline side effects? It is worth your time to know more.

Periphery arterial disease (PAD) is essentially a vascular condition. It mostly occurs in your legs than hands. Hence, a commonly observed sign is painful legs syndrome while you are walking. You may need to rest for a while. You are also likely to experience a few other discomforts such as blue tint on skin, ulceration of skin, abnormal growth of hair on the affected limb. A few people may also witness death of tissues; these complications can lead to amputations or incidence of stroke. In this light, it is essential to know that more than 50% of patients living with PAD may have it without any signs.

Smoking of tobacco products remains as one of the biggest risk factors for PAD. Others in the list are hypertension, onset of diabetes, high level of cholesterol in bloodstream, renal dysfunction, etc. People aged above 40 years are at added risk. Also, if you have experienced prior spells of angina or pain in chest region, you need to consult with your doctor without much delay.

In this milieu, what is pentoxifylline?

This medication is a derivative of xanthine. It is commonly administered for the treatment of muscular pains among individuals living with peripheral arterial diseases. You have some glad news here: this med is available as a generic offering in several parts of the world. This med is mainly taken to manage cramping of muscles, pains, weakness of limbs i.e., hands and legs – these are the typical signs of PAD.

Key ingredients of pentoxifylline helps improve flow of blood. It further enables better supply of oxygen to organs as well as tissues. However, pentoxifylline does not offer a complete cure to conditions like PAD; instead, it helps in the case management of such blood flow-related conditions.

Pentoxifylline long term side effects

This derivative of xanthine may lead to a few side effects. Most commonly encountered adverse effects include discharge of lose stool, flatulence, abdominal discomforts like nausea along with vomiting, feeling dizzy, drowsiness, migraines, etc.

Ensure to stay away from this drug if you have a recent bleed in your cerebral system. Moreover, those who have an internal bleeding in their retina must refrain from taking this drug. Owing to these risks, you need to inform the treating physician of all your ailments.

In some cases, use of pentoxifylline can cause very adverse side effects. If you notice formation of hives, inflammation of facial organs, breathing difficulties, etc. talk to your doctor immediately. On a related note, if you have prior allergies or hypersensitivity to derivatives of xanthine, your caregiving team must be made aware of it.

Upon sensing severe spells of panting, you are advised to call 911 as quickly as possible. Users of pentoxifylline in US can also seek help from the helpdesk of the food and drug administration (FDA). It is a useful thing to know that the FDA has its own helplines to support users of drugs the agency clears.

Users of pentoxifylline in Canada must reach out to Health Canada or visit a poison management center operating closer to where you live. Above all, in order to have a better idea about pentoxifylline side effects, it is a good practice to talk to your caregiver before using this xanthine derivative.

Disclaimer

Information provided here are only of supplementary nature. Information shared here does not substitute a qualified doctor’s advice. This website is not suggesting intake of this drug as safe or appropriate. Hence it is advised to talk to your doctor before consuming this med or any other drug.

Nifedipine dosage

Calcium channel blockers are meds that inhibit the movement of calcium via channels of calcium. These drugs are commonly prescribed for the treatment of high blood pressure. Caregivers find it working well to reduce stiffness of larger blood vessels. In fact, such stiffness remains one of the salient causes for increase in systolic blood pressure levels, especially among elderly people. As an extended use, calcium channel blockers are taken for reducing pain in chest region, caused by onset of angina. Nifedipine is a popular drug in this genre. It is helpful to know more about nifedipine dosage.

Antihypertensive meds are chiefly administered for the management of high blood pressure. If hypertension is left unattended, it can lead to further complications. Conditions such as renal dysfunction, myocardial infraction, cardiac problems, stroke, etc. can arise. Meds belonging to categories like ACE inhibiting drugs, calcium channel blockers, diuretics, etc. are used to control blood pressure.

Of these drugs, calcium channel blockers (CCBs) derive their name from their ability to restrict calcium flow through their channel. Some cells have channels for the flow of calcium through them. Upon receipt of needful signals, these cells let calcium to flow into them. CCBs restrict the widening of these calcium channels and thus reduce the adverse effects. Also, CCBs are known to reduce stiffening of arteries (and veins). This function helps reduce systolic pressure to come down.

In this light, what is nifedipine?

Nifedipine is a CCB used for easing your arteries as well as cardiac muscles. Its easing property helps reduce high blood pressure, pains in chest due to angina, etc. This med can help you to workout / exercise regularly. You are advised to take dosages as per your treatment plan. This drug is however never administered while you are having angina / chest pain. If you are down with angina, your caregiver may prescribe drugs like nitroglycerin as a sublingual offering.

Typical dosage plan is thrice every day. You can take it either before or after food. Strength of nifedipine is dependent on how acute is your clinical condition as well as how your body responds to the initial few doses.

Nifedipine dosage for hypertension

This calcium channel blocker is available as an oral pill. Its strength ranges from 10 milligrams (mg) to 20 mg. It can also be procured an extended-release pill. Here, its strength ranges from 30 mg, 60 mg to 90 mg. Nifedipine dosage for adults is usually pegged at 30 mg, taken once each day. In some acute cases, dosage strength of 60 mg is considered as a starting dose.

In general, your caregiving team may enhance the dosage strength once every week or fortnight. The maximum dose must not breach 120 mg within 24-hour timeline. This drug is not fully studied for being used among children or teens. Owing to likely risks, this medication is never administered to children below 18 years of age.nifedipine-dosage in a wepb image

Nifedipine pregnancy dosage

This is a category C pregnancy medication. This indicates that research done on animals indicate a few adverse outcomes when mothers took this med. Category C also means that adequate number of studies have not been done to ascertain the damages can do to fetus. It becomes an essential thing to tell your caregiver of your pregnancy plans or if you are already pregnant.

This medication must never be used when its likely benefits do not fully justify the likely risks it poses to pregnant women and their fetus. Hence, it is extremely important to tell your doctor if you are already pregnant.

As an added precaution, you need to know that the active ingredients of nifedipine can enter into mother’s milk. This entry can cause a few severe side effects. So, if your health condition requires the intake of nifedipine, you may be advised to stop nursing your infant while you are taking this calcium channel blocker.

Disclaimer

Information provided here are only of supplementary nature. Information shared here does not substitute a qualified doctor’s advice. This website is not suggesting intake of this drug as safe or appropriate. Hence it is advised to talk to your doctor before consuming this med or any other drug.

Minocycline versus doxycycline

Tetracyclines are a genre of meds that come under broad-spectrum antibiotics. These meds derive their name due to the four (i.e., tetra) rings of hydrocarbon in their structure. These came into use in 1940s and soon gained popularity. Their chief function is to inhibit both gram-negative as well as gram-positive bacteria. These meds are known to stop the growth of microbes i.e., bacteriostatic meds; so, they do not kill infection-triggering bacteria. Minocycline and doxycycline are tetracycline antibiotics. On minocycline versus doxycycline – it is a useful to have more inputs.

Tetracyclines are administered to treat infections of the wind pipe and lungs, urinary tract, gastric system, etc. Caregivers use these meds for skin conditions like rosacea and acne. Here, you need to know that tetracyclines are more effective against aerobic bacterial strands. Efficacy of these meds on anaerobic bacteria is not very pronounced.

Tetracyclines can block the synthesis of proteins. These meds have a rare capability to turning effective against both bacterial and viral attacks. Once access to proteins is blocked, microbes find it tough to grow. As a result, their rate of multiplication comes down sizably. In this process, users get needful remedy from infections.

What is minocycline?

This is a tetracycline antibiotic known for its ability to treat a few types of pneumonia, joint conditions such as rheumatoid arthritis and skin conditions like acne. This antibiotic is sold both as a liquid and also as pills. It was launched for public use in the early 1970s. Today, it is available as a generic formulation. It fares among the top 250 widely prescribed drugs in US.

What is doxycycline?

This is also a tetracycline antibiotic, and is known for its broad-spectrum of treatment. Caregiving teams use this drug for treating cholera, chlamydia, acne, pneumonia caused by bacteria, syphilis, typhus – to name a few. As an extended use, doctors use it to prevent the onset of malarial infections. This antibiotic was first marketed in 1960s. You can get doxycycline as a generic med. In terms of prescriptions written, it has crossed 7 million and is ranked among top-100 highly prescribed medications in US.

Minocycline versus doxycycline 

Both drugs belong to the same genre of meds called tetracycline antibiotics. One of the key points of minocycline versus doxycycline is the former has a half-life of nearly 18 hours, and latter’s half-life is ~ 23 hours. Minocycline was approved some 4 years later than doxycycline. This makes doxycycline an earlier entrant into the therapeutic market. In terms of timelines, doxycycline received its approval in the end of 1967; minocycline was approved during mid of 1971.Minocycline-versus-doxycycline in a wep image

Doxycycline is mostly eliminated via feces (about 75%) and the rest is through kidneys. In case of minocycline, feces account for less than 20% of this drug’s elimination from your body with kidneys are responsible for about 11%.

Minocycline may trigger a few autoimmune conditions like vasculitis, hepatitis, lupus, etc. On the other hand, doxycycline may cause gastric side effects. Adverse effects caused in the GI tract by minocycline are not as acute as those triggered by doxycycline. Minocycline is more likely to cause autoimmune and hepatic conditions than doxycycline.

Both these meds are not taken as over the counter drugs. These are to be taken based on the supervision of a caregiver. It is highly recommended to inform your doctor of prior ailments like liver dysfunction prior to taking these antibiotics.

If you sense any severe side effects like inflammation of oral organs like tongue, lips or throat, inform your treating doctor of such undesired outcomes. If you live in US, you need to seek help from the food and drug administration (FDA). Those who live in Canada need to go to a local poison management cell. Lastly, you can get more details about doxycycline versus minocycline by talking to your caregiving team or pharmacist.

Disclaimer

Information provided here are only of supplementary nature. Information shared here does not substitute a qualified doctor’s advice. This website is not suggesting intake of this drug as safe or appropriate. Hence it is advised to talk to your doctor before consuming this med or any other drug.

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