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What is Estriol used for?

Estriol cream is a topical short-term hormone replacement therapy (HRT) used to treat atrophic vaginitis, a vaginal symptom of the menopause. This vaginal cream helps relieve atrophic vaginitis symptoms such as vaginal discharge/dryness/burning/itching, superficial dyspareunia (painful sexual intercourse) and urinary tract infection.

Estriol cream is prescribed for the treatment of estrogen deficiency symptoms. This cream helps restore the natural balance of estrogen in the body, and thus relieves the vaginal symptoms that occur after menopause.

Estriol cream is also used to treat vaginal tissues before and after vaginal surgery (vaginal prolapse) in the postmenopausal women. This medicine may also be used to treat other conditions as determined by your doctor.

What is the recommended dosage of Estriol?

The dosage of Estriol prescribed to each patient will vary. Always follow your physician’s instructions and/or the directions on the prescription drug label.

Estriol cream is for topical use (intravaginal use) only. Apply the cream into the vagina, preferably before going to sleep at night.

What if you miss a dose of Estriol?

If your physician has instructed or directed you to use Estriol medication in a regular schedule and you have missed a dose of this medicine, use it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and go back to your regular dosing schedule. Do not double the doses to catch up for the missed dose.

What if you overdose on Estriol?

Any medication used in excess can have serious consequences. If you suspect an overdose of Estriol, seek medical attention immediately.

Symptoms of overdose of Estriol may include vaginal bleeding.

What other drugs could interact with Estriol?

It may be noted that drugs other than those listed above may also interact with Estriol.

Estriol can interact with the following types of medicines: anti-epileptic medicines, barbiturates, corticosteroids, anti-infectives, HIV medicines, rifamycin antibiotics, and anticoagulants.

Usually drug interactions occur when it is used with another drug or with food. Before you take a medication for a particular ailment, you should inform the health expert about intake of any other medications including non-prescription medications (over-the-counter products) and dietary supplements like vitamins, minerals and herbal, which may increase the effect of Estriol, so that the doctor can warn you of any possible drug interactions.

Do let your doctor know if you smoke, consume alcohol or caffeinated drinks, or use illegal drugs as these may interfere with the action of your medication. Make sure to inform your doctor of any medical conditions you may have, or any family history of medical problems. Do not start or stop using any medicine without consulting your doctor.

What are the side effects of Estriol?

Like other medicines, Estriol can cause some side effects. If they do occur, the side effects of Estriol are most likely to be minor and temporary. However, some may be serious and may require the individual to inform the doctor or visit the nearest hospital immediately.

It is pertinent to note that side effects of Estriol cannot be anticipated. If any side effects of Estriol develop or change in intensity, the doctor should be informed as soon as possible.

Estriol can cause side effects such as breast tenderness, increased vaginal discharge, and irritation/itching at the application site. This is not a complete list of all side effects. Do concur with your doctor and follow his directions completely when you are using Estriol.

What are the questions to ask your doctor before taking Estriol?

Is it possible for me to use Estriol with other drugs?
Should certain beverages, foods and other products be avoided when I use Estriol?
What are the possible drug interactions of Estriol?
How will Estriol work in my body?
How should Estriol be used?
How to reduce the risk of Estriol drug interactions and side effects?


Estriol cream should not be used during pregnancy.

Before using Estriol cream, inform your doctor or pharmacist if you have uterine fibroids, high blood pressure, heart/liver/kidney disorders, diabetes, migraine, asthma, epilepsy, gall stones and endometriosis.

The health and medical information provided here is intended to supplement and not substitute for the expertise and judgment of your physician, pharmacists or other health care professional. It should not be understood to indicate that the use of Estriol is safe, appropriate or effective for you. Always consult your health care professional before using this, or any other, drug.


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