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What does Fludrocortisone treat?

Fludrocortisone comes under the class of corticosteroids. The adrenal gland naturally generates glucocorticoid. However, in patients whose glucocorticoid levels fall low due to conditions such as Addison's disease, salt-losing adrenogenital syndrome and adrenocortical insufficiency, Fludrocortisone steps in to replenish the glucocorticoid levels.

Possible Side Effects

Fludrocortisone might have some side effects but it’s not possible to anticipate them. It does not have any major side effects and the minor ones that may occur are temporary. In rare cases, there might be major side effects and immediate medical attention must be sought.

Some of the side effects are stomach upset, fluid retention, headache, vomiting, dizziness, skin problems, depression, sleeping problems and anxiety. This is not the complete list though.

In case, there is a change in intensity of side effects or if any new side effects develop, make sure you consult your doctor.

Dosage Instructions

Follow the Fludrocortisone dosage prescribed by your physician. The dosage could vary based on individual patient requirements. Always follow your physician’s instructions or go by the directions on the prescription drug label.

Missed a dose?

Take it immediately once you remember. In case, this time is closer to the next dosage, skip it and get back to the prescribed schedule. Never take a double dose unless specifically instructed by your doctor.


Don’t waste any time and seek immediate medical attention.

Drug Interactions

Drug interactions must be considered before starting to take any kind of drug. Drug interactions might happen either when Fludrocortisone is taken along with another drug or when taken with particular foods. To prevent any kind of negative interaction, make sure you inform your doctor of any drugs you are taking including non-prescription medication, OTCs, health supplements like vitamins, minerals, herbal medicine and so on which may interfere with the effect of Fludrocortisone.

It may interact with: 

  • Albuterol/Salbutamol 
  • Ebastine-Phenylephrine

It may also interact with birth control pills, blood thinners and diabetes medications. This is not an exhaustive list though.

Appraise your doctor of any medical conditions that you are suffering from and your family history of medical ailments. It’s important that you do not stop or start taking any medicine without the consent of your physician.

What Is the difference between Fludrocortisone vs Hydrocortisone?

Hydrocortisone medication is a good topical steroid for trying to treat some minor rashes or skin irritation. Whereas, Fludrocortisone medication is an effective in correcting electrolyte imbalances associated with Addison's disease.

What Is the Fludrocortisone mechanism of action?

Fludrocortisone medicine is known to be a corticosteroid, which is used to help and control the amount of sodium fluids in the body. This Fludrocortisone over the counter medicine is used to treat Addison's disease and syndromes where excessive amounts of sodium are lost in the urine. The medication Fludrocortisone without prescription works by decreasing the amount of sodium that is lost (excreted) in the urine.

What are the Fludrocortisone contraindications?

Fludrocortisone over the counter tablets is contraindicated in patients with systemic fungal infections and in those who are having a history of possible or known hypersensitivity to some of these agents.

Fludrocortisone Reviews

  • This medication is just so miraculous. I have POTS, and with this solution all of a sudden, I was able to function somewhat. This medicine helps me put life back in my eyes. The pills are small and easy for consumption. I am able to attend college, when I was barely able to stay awake during high school
  • I use this medication for POTS (postural orthostatic tachycardia syndrome)/ dysautonomia that many people might seem to have on here and not know about it, and it has helped me immensely. I would not function day to day without it and I do not even faint from my issue of POTS
  • I have had addison's disease for approx. 3 years now and have been taking fludrocortisone and hydrocortisone since being diagnosed about the condition. No bad side effects for me, energy level has enhanced by 100%, along with mental and cognitive function. Very pleased with the results of this medication!
  • I've taken fludrocortisone for almost 10 years now. It has helped me a lot with orthostatic hypotension. Questionable impact on breathlessness with some sort of exertion or mental fogginess. It might not need to monitor blood pressure. The medication can lead to BP to be above normal, healthy levels

Where can I buy Fludrocortisone over the counter?

Fludrocortisone with prescription is not possible as this medication is a prescription solution which is used to treat the symptoms of Addison Disease (Adrenocortical Insufficiency) and Salt-Losing Forms of Congenital Adrenogenital Syndrome like condition. This Fludrocortisone over the counter is to be used alone or with other medications.

Can I buy Fludrocortisone without a prescription?

Fludrocortisone over the counter medication is a prescription solution that is used for the treatment of Addison Disease (Adrenocortical Insufficiency) and Salt-Losing Forms of Congenital Adrenogenital Syndrome. Fludrocortisone may be used alone or with other medications for that reason.

What to ask your doctor before you start on Fludrocortisone

  • Can I take Fludrocortisone along with other drugs?
  • Are there certain foods, beverages and products to be avoided while on Fludrocortisone?
  • What is the dosage of Fludrocortisone to be consumed?
  • How should I use Fludrocortisone?
  • How will Fludrocortisone work in my body?
  • How can the drug interactions and side effects of Fludrocortisone be minimized or completely avoided?


The health and medical information that we have provided are meant to supplement and not substitute the advice of your physician, pharmacists or other health care professionals. This does not suggest that usage of Fludrocortisone is safe, appropriate or effective for you. Always ensure that you take this or any other drug only after consulting your physician.


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