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What is Glimepiride used for?

Glimepiride is an oral medication used to lower blood glucose levels in type 2 diabetes (non-insulin-dependent diabetes) patients. This medication is prescribed when high levels of blood sugar cannot be controlled by diet and exercise alone. It belongs to sulfonylurea class of diabetic drugs, which works by stimulating the pancreas to produce more insulin. This medicine may also be used to treat other conditions as determined by your doctor.

What is the recommended dosage of Glimepiride?

The dosage of Glimepiride prescribed to each patient will vary. Always follow your physician’s instructions and/or the directions on the prescription drug label.

Glimepiride is usually taken once a day along with breakfast. Take the medication with a full glass of water.

What if you miss a dose of Glimepiride?

If your physician has instructed or directed you to take Glimepiride medication in a regular schedule and you have missed a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and go back to your regular dosing schedule. Do not double the doses unless otherwise directed.

What if you overdose on Glimepiride?

Any medication taken in excess can have serious consequences. If you suspect an overdose of Glimepiride, seek medical attention immediately. Some of the overdose symptoms of this drug are cold sweats, loss of consciousness, anxiety, hunger, nausea, and drowsiness.

What other drugs could interact with Glimepiride?

It may be noted that drugs other than those listed above may also interact with Glimepiride.

Usually drug interactions occur when it is taken with another drug or with food. Before you take a medication for a particular ailment, you should inform the health expert about intake of any other medications including non-prescription medications, over-the-counter medicines that may increase the effect of Glimepiride, and dietary supplements like vitamins, minerals and herbal, so that the doctor can warn you of any possible drug interactions.

Glimepiride can interact with heart and blood pressure medications, diuretics, corticosteroids, oral contraceptives, estrogens, thyroid medications, sulfa drugs, MAO inhibitors, and nonsteroidal anti-inflammatory drugs.

Do let your doctor know if you smoke, consume alcohol or caffeinated drinks, or use illegal drugs as these may interfere with the action of your medication. Make sure to inform your doctor of any medical conditions you may have, or any family history of medical problems. Do not start or stop using any medicine without consulting your doctor.

What are the side effects of Glimepiride?

Like other medicines, Glimepiride can cause some side effects. If they do occur, the side effects of Glimepiride are most likely to be minor and temporary. However, some may be serious and may require the individual to inform the doctor or visit the nearest hospital immediately.

It is pertinent to note that side effects of Glimepiride cannot be anticipated. If any side effects of Glimepiride develop or change in intensity, the doctor should be informed as soon as possible.

Glimepiride can cause side effects such as blurred vision, vomiting, diarrhea, dizziness, headache, nausea, sensitivity to light, and stomach pain. Some of the serious side effects of this drug include shortness of breath, dark urine, convulsions, rapid weight gain, difficulty breathing, chest tightness, jaundice, and swelling of the mouth, face, lips, or tongue. This is not a complete list of all side effects. Do concur with your doctor and follow his directions completely when you are taking Glimepiride.

What are the questions to ask your doctor before taking Glimepiride?

Is it possible for me to take Glimepiride with other drugs?
Should certain beverages, foods and other products be avoided when I take Glimepiride?
What are the possible drug interactions of Glimepiride?
How will Glimepiride work in my body?
How should Glimepiride be taken?
How to reduce the risk of Glimepiride drug interactions and side effects?


The health and medical information provided here is intended to supplement and not substitute for the expertise and judgment of your physician, pharmacists or other health care professional. Before taking Glimepiride, inform your doctor if you are pregnant, planning to become pregnant, or are breast-feeding. Also, you need to inform if you have heart disease, liver or kidney problems, intestinal problems, and thyroid problems.


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