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What is Glyburide/Glibenclamide–Metformin used for?

Glyburide/Glibenclamide–Metformin is an anti-diabetic medicine that helps control blood sugar levels in patients with type 2 diabetes (non-insulin-dependent diabetes). It is a combination of two oral diabetes medicines, Glyburide/Glibenclamide and Metformin, which works by stimulating the release of your body's natural insulin. It is used along with a diet and exercise program to lower high blood sugar in patients. By controlling high blood sugar, Glyburide/Glibenclamide–Metformin helps prevent kidney disease, heart disease, nerve problems, strokes, impotence, and blindness. This medicine may also be used to treat other conditions as determined by your doctor.

What is the recommended dosage of Glyburide/Glibenclamide–Metformin?

The dosage of Glyburide/Glibenclamide–Metformin prescribed to each patient will vary. Always follow your physician’s instructions and/or the directions on the prescription drug label.

Take Glyburide/Glibenclamide–Metformin with meals.

What if you miss a dose of Glyburide/Glibenclamide–Metformin?

If your physician has instructed or directed you to take Glyburide/Glibenclamide–Metformin medication in a regular schedule and you have missed a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and go back to your regular dosing schedule. Do not double the doses unless otherwise directed.

What if you overdose on Glyburide/Glibenclamide–Metformin?

Any medication taken in excess can have serious consequences. If you suspect an overdose of Glyburide/Glibenclamide–Metformin, seek medical attention immediately.

What other drugs could interact with Glyburide/Glibenclamide–Metformin?

It may be noted that drugs other than those listed above may also interact with Glyburide/Glibenclamide–Metformin.

Usually drug interactions occur when it is taken with another drug or with food. Before you take a medication for a particular ailment, you should inform the health expert about intake of any other medications including non-prescription medications, over-the-counter medicines that may increase the effect of Glyburide/Glibenclamide–Metformin, and dietary supplements like vitamins, minerals and herbal, so that the doctor can warn you of any possible drug interactions.

Glyburide/Glibenclamide–Metformin can interact with steroids, thyroid medicines, and diuretics.

Do let your doctor know if you smoke, consume alcohol or caffeinated drinks, or use illegal drugs as these may interfere with the action of your medication. Make sure to inform your doctor of any medical conditions you may have, or any family history of medical problems. Do not start or stop using any medicine without consulting your doctor.

What are the side effects of Glyburide/Glibenclamide–Metformin?

Like other medicines, Glyburide/Glibenclamide–Metformin can cause some side effects. If they do occur, the side effects of Glyburide/Glibenclamide–Metformin are most likely to be minor and temporary. However, some may be serious and may require the individual to inform the doctor or visit the nearest hospital immediately.

It is pertinent to note that side effects of Glyburide/Glibenclamide–Metformin cannot be anticipated. If any side effects of Glyburide/Glibenclamide–Metformin develop or change in intensity, the doctor should be informed as soon as possible.

Glyburide/Glibenclamide–Metformin can cause side effects such as sneezing, runny nose, headache, dizziness, mild nausea, vomiting, diarrhea, and stomach pain. This is not a complete list of all side effects. Do concur with your doctor and follow his directions completely when you are taking Glyburide/Glibenclamide–Metformin.

What are the questions to ask your doctor before taking Glyburide/Glibenclamide–Metformin?

Is it possible for me to take Glyburide/Glibenclamide–Metformin with other drugs?
Should certain beverages, foods and other products be avoided when I take Glyburide/Glibenclamide–Metformin?
What are the possible drug interactions of Glyburide/Glibenclamide–Metformin?
How will Glyburide/Glibenclamide–Metformin work in my body?
How should Glyburide/Glibenclamide–Metformin be taken?
How to reduce the risk of Glyburide/Glibenclamide–Metformin drug interactions and side effects?


The health and medical information provided here is intended to supplement and not substitute for the expertise and judgment of your physician, pharmacists or other health care professional. It should not be understood to indicate that the use of Glyburide/Glibenclamide–Metformin is safe, appropriate or effective for you. Always consult your health care professional before using this, or any other, drug.


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