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Isosorbide Dinitrate–Hydralazine
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What is Isosorbide Dinitrate–Hydralazine used for?

Isosorbide Dinitrate–Hydralazine is a fixed dose combination medication used to treat heart failure. This drug contains 2 medicines, Isosorbide Dinitrate and Hydralazine, which are called vasodilators. Isosorbide Dinitrate–Hydralazine works by relaxing arteries and veins (blood vessels), which causes the heart to pump blood more easily.

In heart failure patients, Isosorbide Dinitrate–Hydralazine is prescribed in addition to standard treatment. This medicine may also be used to treat other conditions as determined by your doctor.

What is the recommended dosage of Isosorbide Dinitrate–Hydralazine

The dosage of Isosorbide Dinitrate–Hydralazine prescribed to each patient will vary. Always follow your physician’s instructions and/or the directions on the prescription drug label.

Take each dose of Isosorbide Dinitrate–Hydralazine with a full glass of water.

What if you miss a dose of Isosorbide Dinitrate–Hydralazine?

If your physician has instructed or directed you to take Isosorbide Dinitrate–Hydralazine medication in a regular schedule and you have missed a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and go back to your regular dosing schedule. Do not double the doses to catch up for the missed dose.

What if you overdose on Isosorbide Dinitrate–Hydralazine?

Any medication taken in excess can have serious consequences. If you suspect an overdose of Isosorbide Dinitrate–Hydralazine, seek medical attention immediately. Overdose symptoms of Isosorbide Dinitrate–Hydralazine may include severe headache, changes in vision, nausea, vomiting, chest pain, irregular heartbeat, confusion, sweating and flushing.

What other drugs could interact with Isosorbide Dinitrate–Hydralazine?

It may be noted that drugs other than those listed above may also interact with Isosorbide Dinitrate–Hydralazine.

Isosorbide Dinitrate–Hydralazine can interact with the following types of medicines: high blood pressure medications, monoamine oxidase (MAO) inhibitors, erectile dysfunction medicines, beta-blockers and certain headache drugs.

Usually drug interactions occur when it is taken with another drug or with food. Before you take a medication for a particular ailment, you should inform the health expert about intake of any other medications including non-prescription medications (over-the-counter products) and dietary supplements like vitamins, minerals and herbal, which may increase the effect of Isosorbide Dinitrate–Hydralazine, so that the doctor can warn you of any possible drug interactions.

Do let your doctor know if you smoke, consume alcohol or caffeinated drinks, or use illegal drugs as these may interfere with the action of your medication. Make sure to inform your doctor of any medical conditions you may have, or any family history of medical problems. Do not start or stop using any medicine without consulting your doctor.

What are the side effects of Isosorbide Dinitrate–Hydralazine?

Like other medicines, Isosorbide Dinitrate–Hydralazine can cause some side effects. If they do occur, the side effects of Isosorbide Dinitrate–Hydralazine are most likely to be minor and temporary. However, some may be serious and may require the individual to inform the doctor or visit the nearest hospital immediately.

It is pertinent to note that side effects of Isosorbide Dinitrate–Hydralazine cannot be anticipated. If any side effects of Isosorbide Dinitrate–Hydralazine develop or change in intensity, the doctor should be informed as soon as possible.

Isosorbide Dinitrate–Hydralazine can cause side effects such as nausea, vomiting, dizziness, headache, flushing and lightheadedness. Some of the serious side effects of Isosorbide Dinitrate–Hydralazine may include fever, persistent fatigue, rash and irregular heartbeat. This is not a complete list of all side effects. Do concur with your doctor and follow his directions completely when you are taking Isosorbide Dinitrate–Hydralazine.

What are the questions to ask your doctor before taking Isosorbide Dinitrate–Hydralazine?

Is it possible for me to use Difluprednate with other drugs?
Should certain beverages, foods and other products be avoided when I use Difluprednate?
What are the possible drug interactions of Difluprednate?
How will Difluprednate work in my body?
How should Difluprednate be used?
How to reduce the risk of Difluprednate drug interactions and side effects?


The health and medical information provided here is intended to supplement and not substitute for the expertise and judgment of your physician, pharmacists or other health care professional. It should not be understood to indicate that the use of Difluprednate is safe, appropriate or effective for you. Always consult your health care professional before using this, or any other, drug.

Before using Difluprednate, inform your doctor if you have glaucoma or cataract. As Difluprednate may cause blurred vision, be careful while driving.


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