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What is Lubiprostone used for?

Lubiprostone is an oral medication indicated for the treatment of chronic idiopathic constipation (CIC) in adults. CIC means infrequency or difficulty in passing stool, which has an unknown cause and is not due to an underlying disease, medication, or diet. This medicine may also be used to treat other conditions as determined by your doctor.

Lubiprostone is also used in the treatment of irritable bowel syndrome with constipation in women. It works by increasing the secretion of fluid within your intestines, which helps in the easy passage of stools. This medicine belongs to a class of drugs known as chloride channel activators.

What is the recommended dosage of Lubiprostone?

The dosage of Lubiprostone prescribed to each patient will vary. Always follow your physician’s instructions and/or the directions on the prescription drug label.

Take Lubiprostone by mouth with food. Take the medicine with a full glass of water.

What if you miss a dose of Lubiprostone?

If your physician has instructed or directed you to take Lubiprostone medication in a regular schedule and you have missed a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and go back to your regular dosing schedule. Do not double the doses unless otherwise directed.

What if you overdose on Lubiprostone?

Any medication taken in excess can have serious consequences. If you suspect an overdose of Lubiprostone, seek medical attention immediately.

What other drugs could interact with Lubiprostone?

Usually drug interactions occur when it is taken with another drug or with food. Before you take a medication for a particular ailment, you should inform the health expert about intake of any other medications including non-prescription medications, over-the-counter medicines that may increase the effect of Lubiprostone, and dietary supplements like vitamins, minerals and herbal, so that the doctor can warn you of any possible drug interactions.

Do let your doctor know if you smoke, consume alcohol or caffeinated drinks, or use illegal drugs as these may interfere with the action of your medication. Make sure to inform your doctor of any medical conditions you may have, or any family history of medical problems. Do not start or stop using any medicine without consulting your doctor.

What are the side effects of Lubiprostone?

Like other medicines, Lubiprostone can cause some side effects. If they do occur, the side effects of Lubiprostone are most likely to be minor and temporary. However, some may be serious and may require the individual to inform the doctor or visit the nearest hospital immediately.

It is pertinent to note that side effects of Lubiprostone cannot be anticipated. If any side effects of Lubiprostone develop or change in intensity, the doctor should be informed as soon as possible.

Lubiprostone can cause side effects such as nausea, vomiting, mild diarrhea, gas, cough, and headache. This is not a complete list of all side effects. Do concur with your doctor and follow his directions completely when you are taking Lubiprostone.

What are the questions to ask your doctor before taking Lubiprostone?

Is it possible for me to take Lubiprostone with other drugs?
Should certain beverages, foods and other products be avoided when I take Lubiprostone?
What are the possible drug interactions of Lubiprostone?
How will Lubiprostone work in my body?
How should Lubiprostone be taken?
How to reduce the risk of Lubiprostone drug interactions and side effects?


The health and medical information provided here is intended to supplement and not substitute for the expertise and judgment of your physician, pharmacists or other health care professional. It should not be understood to indicate that the use of Lubiprostone is safe, appropriate or effective for you. Always consult your health care professional before using this, or any other, drug.


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