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What is Neostigmine used for?

Neostigmine is indicated to treat the symptoms of myasthenia gravis (a muscle weakness disorder). Neostigmine belongs to a group of medicines called anticholinesterases. Neostigmine works by prolonging the action of acetylcholine (a natural substance) in the body and this improves the strength of muscles in patients with myasthenia gravis.

Neostigmine may also be used to treat other conditions as determined by your doctor.

What are the side effects of Neostigmine?

Like other medicines, Neostigmine can cause some side effects. If they do occur, the side effects of Neostigmine are most likely to be minor and temporary. However, some may be serious and may require the individual to inform the doctor or visit the nearest hospital immediately.

It is pertinent to note that side effects of Neostigmine cannot be anticipated. If any side effects of Neostigmine develop or change in intensity, the doctor should be informed as soon as possible.

Neostigmine can cause side effects such as nausea, vomiting, diarrhea, dilation of pupils, increased salivation, increased sweating, frequent urination and dizziness. This is not a complete list of all side effects. Do concur with your doctor and follow his directions completely when you are taking Neostigmine.

What is the recommended dosage of Neostigmine?

The dosage of Neostigmine prescribed to each patient will vary. Always follow your physician’s instructions and/or the directions on the prescription drug label.

Take Neostigmine tablet by mouth with or without food.

What if you miss a dose of Neostigmine?

If your physician has instructed or directed you to take Neostigmine medication in a regular schedule and you have missed a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and go back to your regular dosing schedule. Do not double the doses to catch up for the missed dose.

What if you overdose on Neostigmine?

Any medication taken in excess can have serious consequences. If you suspect an overdose of Neostigmine, seek medical attention immediately.

Overdose symptoms of Neostigmine may include nausea, vomiting, diarrhea, stomach cramps, excessive saliva and blurred vision.

What other drugs could interact with Neostigmine?

It may be noted that drugs other than those listed above may also interact with Neostigmine.

Neostigmine can interact with the following types of medicines: aminoglycoside antibiotics, beta-blockers, heart rhythm medications, antispasmodics and corticosteroids.

Usually drug interactions occur when it is taken with another drug or with food. Before you take a medication for a particular ailment, you should inform the health expert about intake of any other medications including non-prescription medications (over-the-counter products) and dietary supplements like vitamins, minerals and herbal, which may increase the effect of Neostigmine, so that the doctor can warn you of any possible drug interactions.

Do let your doctor know if you smoke, consume alcohol or caffeinated drinks, or use illegal drugs as these may interfere with the action of your medication. Make sure to inform your doctor of any medical conditions you may have, or any family history of medical problems. Do not start or stop using any medicine without consulting your doctor.

What are the questions to ask your doctor before taking Neostigmine?

Is it possible for me to take Neostigmine with other drugs?
Should certain beverages, foods and other products be avoided when I take Neostigmine?
What are the possible drug interactions of Neostigmine?
How will Neostigmine work in my body?
How should Neostigmine be taken?
How to reduce the risk of Neostigmine drug interactions and side effects?


Before taking Neostigmine, tell your doctor if you have an overactive thyroid, heart problems, stomach problems, asthma, epilepsy, Parkinson's disease, low blood pressure, slow heart rate and vagotonia (a nerve disorder). Also, tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding.

The health and medical information provided here is intended to supplement and not substitute for the expertise and judgment of your physician, pharmacists or other health care professional. It should not be understood to indicate that the use of Neostigmine is safe, appropriate or effective for you. Always consult your health care professional before using this, or any other, drug.


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