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What is Pioglitazone–Metformin used for?

Pioglitazone–Metformin is a oral diabetic medicine used to control blood sugar levels in people with type 2 diabetes. This drug is a combination medication composed of ingredients namely pioglitazone and metformin, which reduces blood glucose levels as well as amount of sugar absorbed into the body. Thus, in combination with proper diet and exercise, Pioglitazone–Metformin reduces the diabetic complications such as eye, kidney, nerve, and sexual function problems. This medicine may also be used to treat other conditions as determined by your doctor.

What is the recommended dosage of Pioglitazone–Metformin?

The dosage of Pioglitazone–Metformin prescribed to each patient will vary. Always follow your physician’s instructions and/or the directions on the prescription drug label.

Take Pioglitazone–Metformin by mouth along with a meal. It is usually taken once or twice daily. Use this medicine regularly to obtain its maximum benefit. It is important that you take the medicine at the same time each day in order to maintain consistent sugar levels in your blood stream.

What if you miss a dose of Pioglitazone–Metformin?

If your physician has instructed or directed you to take Pioglitazone–Metformin medication in a regular schedule and you have missed a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and go back to your regular dosing schedule. Do not double the doses unless otherwise directed.

What if you overdose on Pioglitazone–Metformin?

Any medication taken in excess can have serious consequences. If you suspect an overdose of Pioglitazone–Metformin, seek medical attention immediately. Some of the overdose symptoms of this drug are low blood sugar and lactic acidosis, which may lead to hunger, confusion, irritability, drowsiness, headache, tremors, sweating, fast heartbeat, weakness, muscle pain, shortness of breath, stomach pain, light-headedness, blurry vision, and seizures.

What other drugs could interact with Pioglitazone–Metformin?

It may be noted that drugs other than those listed above may also interact with Pioglitazone–Metformin.

Usually drug interactions occur when it is taken with another drug or with food. Before you take a medication for a particular ailment, you should inform the health expert about intake of any other medications including non-prescription medications, over-the-counter medicines that may increase the effect of Pioglitazone–Metformin, and dietary supplements like vitamins, minerals and herbal, so that the doctor can warn you of any possible drug interactions.

Pioglitazone–Metformin can interact with other diabetic medications, calcium channel blockers, corticosteroids, thiazide diuretics, thyroid medications, estrogens, oral contraceptives, decongestants, and nicotine replacement medications.

Do let your doctor know if you smoke, consume alcohol or caffeinated drinks, or use illegal drugs as these may interfere with the action of your medication. Make sure to inform your doctor of any medical conditions you may have, or any family history of medical problems. Do not start or stop using any medicine without consulting your doctor.

What are the side effects of Pioglitazone–Metformin?

Like other medicines, Pioglitazone–Metformin can cause some side effects. If they do occur, the side effects of Pioglitazone–Metformin are most likely to be minor and temporary. However, some may be serious and may require the individual to inform the doctor or visit the nearest hospital immediately.

It is pertinent to note that side effects of Pioglitazone–Metformin cannot be anticipated. If any side effects of Pioglitazone–Metformin develop or change in intensity, the doctor should be informed as soon as possible.

The common side effects of Pioglitazone–Metformin are upper respiratory tract infections, diarrhea, nausea, urinary tract infections, dizziness, headache, weakness, muscle pain, stomach pain, light-headedness, and fainting. Some of the serious side effects of this drug include shortness of breath, dark urine, and swelling of your face, lips, tongue, or throat.

What are the questions to ask your doctor before taking Pioglitazone–Metformin?

Is it possible for me to take Pioglitazone–Metformin with other drugs?
Should certain beverages, foods and other products be avoided when I take Pioglitazone–Metformin?
What are the possible drug interactions of Pioglitazone–Metformin?
How will Pioglitazone–Metformin work in my body?
How should Pioglitazone–Metformin be taken?
How to reduce the risk of Pioglitazone–Metformin drug interactions and side effects?


The health and medical information provided here is intended to supplement and not substitute for the expertise and judgment of your physician, pharmacists or other health care professional. Before using Pioglitazone–Metformin, inform your doctor or healthcare professional if you have serious infection, liver disease, kidney disease, eye problems, recent heart attack, recent stroke, type 1 diabetes, severe breathing problems, and fertility problems. Caution needs to be exercised while driving or handling machinery.


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