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What is Prasugrel used for?

Prasugrel is an antiplatelet medicine used to prevent blood clots forming in patients with acute coronary syndrome (heart attack, unstable angina), who have been treated with a certain heart procedure called angioplasty (percutaneous coronary intervention or PCI). Prasugrel is normally taken in combination with aspirin.

Prasugrel belongs to the thienopyridine class of medicines. Prasugrel works by blocking platelets (sticky blood cells) from clumping together inside the arteries of your heart (or cardiac stent) and thus helps reduce the risk of blood clots. This effect helps maintain the smooth flow of blood in your body and can prevent heart problems again in the future.

Prasugrel may also be used to treat other conditions as determined by your doctor.

What is the recommended dosage of Prasugrel?

The dosage of Prasugrel prescribed to each patient will vary. Always follow your physician’s instructions and/or the directions on the prescription drug label.

Prasugrel medicine is taken one time each day. Take Prasugrel with a full glass of water, with or without food.

What if you miss a dose of Prasugrel?

If your physician has instructed or directed you to take Prasugrel medication in a regular schedule and you have missed a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and go back to your regular dosing schedule. Do not double the doses to catch up for the missed dose.

What if you overdose on Prasugrel?

Any medication taken in excess can have serious consequences. If you suspect an overdose of Prasugrel, seek medical attention immediately.

Overdose symptoms of Prasugrel may include blurred vision, watery eyes, trouble walking, shortness of breath, vomiting and bleeding complications.

What other drug(s) could interact with Prasugrel?

It may be noted that drugs other than those listed above may also interact with Prasugrel.

Prasugrel can interact with the following types of medicines: other antiplatelet medications, fibrinolytics and non-steroidal anti-inflammatory drugs (NSAIDs).

Usually drug interactions occur when it is taken with another drug or with food. Before you take a medication for a particular ailment, you should inform the health expert about intake of any other medications including non-prescription medications (over-the-counter products) and dietary supplements like vitamins, minerals and herbal, which may increase the effect of Prasugrel, so that the doctor can warn you of any possible drug interactions.

Do let your doctor know if you smoke, consume alcohol or caffeinated drinks, or use illegal drugs as these may interfere with the action of your medication. Make sure to inform your doctor of any medical conditions you may have, or any family history of medical problems. Do not start or stop using any medicine without consulting your doctor.

What are the side effects of Prasugrel?

Like other medicines, Prasugrel can cause some side effects. If they do occur, the side effects of Prasugrel are most likely to be minor and temporary. However, some may be serious and may require the individual to inform the doctor or visit the nearest hospital immediately.

It is pertinent to note that side effects of Prasugrel cannot be anticipated. If any side effects of Prasugrel develop or change in intensity, the doctor should be informed as soon as possible.

Prasugrel can cause side effects such as headache, diarrhea, bleeding, nausea, dizziness, tiredness, cough and back pain. This is not a complete list of all side effects. Do concur with your doctor and follow his directions completely when you are taking Prasugrel.

What are the questions to ask your doctor before taking Prasugrel?

Is it possible for me to take Prasugrel with other drugs?
Should certain beverages, foods and other products be avoided when I take Prasugrel?
What are the possible drug interactions of Prasugrel?
How will Prasugrel work in my body?
How should Prasugrel be taken?
How to reduce the risk of Prasugrel drug interactions and side effects?

What other important information should you know about Prasugrel?

Before taking Prasugrel, make sure to tell your doctor if you

  • have had a stroke or a transient ischemic attack
  • have severe liver problems
  • have active bleeding (intestinal bleeding)
  • are to undergo a surgery
  • weigh less than 60kg.

Also, tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding.


The health and medical information provided here is intended to supplement and not substitute for the expertise and judgment of your physician, pharmacists or other health care professional. It should not be understood to indicate that the use of Prasugrel is safe, appropriate or effective for you. Always consult your health care professional before using this, or any other, drug.


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