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What is Pyrazinamide 500mg (PZA) used for?

Pyrazinamide 500mg (PZA) is an antibiotic used to treat tuberculosis (TB). This medication kills or stops the growth of bacteria that causes tuberculosis. It is often used in combination with other anti-tuberculosis medications. This medicine may also be used to treat other conditions as determined by your doctor.

What are the side effects of Pyrazinamide 500mg (PZA)?

Like other medicines, Pyrazinamide 500mg (PZA) can cause some side effects. If they do occur, the side effects of Pyrazinamide are most likely to be minor and temporary. However, some may be serious and may require the individual to inform the doctor or visit the nearest hospital immediately.

It is pertinent to note that side effects of Pyrazinamide cannot be anticipated. If any side effects of Pyrazinamide develop or change in intensity, the doctor should be informed as soon as possible.

Pyrazinamide can cause side effects such as stomach upset, vomiting, loss of appetite, acne, and skin rash. This is not a complete list of all side effects. Do concur with your doctor and follow his directions completely when you are taking Pyrazinamide.

What is the recommended dosage of Pyrazinamide?

The dosage of Pyrazinamide prescribed to each patient will vary. Always follow your physician’s instructions and/or the directions on the prescription drug label.

Pyrazinamide can be taken with or without food.

What if you miss a dose of Pyrazinamide?

If your physician has instructed or directed you to take Pyrazinamide medication in a regular schedule and you have missed a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and go back to your regular dosing schedule. Do not double the doses unless otherwise directed.

What if you overdose on Pyrazinamide?

Any medication taken in excess can have serious consequences. If you suspect an overdose of Pyrazinamide, seek medical attention immediately.

What other drugs could interact with Pyrazinamide 500mg (PZA)?

It may be noted that drugs other than that listed above may also interact with Pyrazinamide.

Usually drug interactions occur when it is taken with another drug or with food. Before you take a medication for a particular ailment, you should inform the health expert about intake of any other medications including non-prescription medications, over-the-counter medicines that may increase the effect of Pyrazinamide, and dietary supplements like vitamins, minerals and herbal, so that the doctor can warn you of any possible drug interactions.

Do let your doctor know if you smoke, consume alcohol or caffeinated drinks, or use illegal drugs as these may interfere with the action of your medication. Make sure to inform your doctor of any medical conditions you may have, or any family history of medical problems. Do not start or stop using any medicine without consulting your doctor.

What are the questions to ask your doctor before taking Pyrazinamide 500mg (PZA) tablet?

Is it possible for me to take Pyrazinamide with other drugs?
Should certain beverages, foods and other products be avoided when I take Pyrazinamide?
What are the possible drug interactions of Pyrazinamide?
How will Pyrazinamide work in my body?
How should Pyrazinamide be taken?
How to reduce the risk of Pyrazinamide drug interactions and side effects?


The health and medical information provided here is intended to supplement and not substitute for the expertise and judgment of your physician, pharmacists or other health care professional. It should not be understood to indicate that the use of Pyrazinamide is safe, appropriate or effective for you. Always consult your health care professional before using this, or any other, drug.


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