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What is Ranolazine used for?

Ranolazine is an anti-anginal medication prescribed to treat chronic angina. The symptoms of angina are discomfort and pain in the chest, which is caused by inadequate blood flow in the heart. Ranolazine is an extended release anti-ischemic drug that helps in reducing the angina attacks by improving the flow of blood in the heart. This medicine works without lowering the blood pressure levels. It is used in combination with amlodipine, beta-blockers or nitrates. In particular, Ranolazine is prescribed for the chronic angina patients who have not responded to the angina therapy given initially. This medicine may also be used to treat other conditions as determined by your doctor.

What are the side effects of Ranolazine?

Like other medicines, Ranolazine can cause some side effects. If they do occur, the side effects of Ranolazine are most likely to be minor and temporary. However, some may be serious and may require the individual to inform the doctor or visit the nearest hospital immediately.

It is pertinent to note that side effects of Ranolazine cannot be anticipated. If any side effects of Ranolazine develop or change in intensity, the doctor should be informed as soon as possible.

Ranolazine can cause side effects such as dizziness, headache, constipation, blurred vision, vomiting, dry mouth, and ringing in ears. Some of the serious side effects of this drug are swelling in your hands, ankles, or feet; pain; bruising; severe tingling; shortness of breath; and blood in urine. This is not a complete list of all side effects. Do concur with your doctor and follow his directions completely when you are taking Ranolazine.

What is the recommended dosage of Ranolazine?

The dosage of Ranolazine prescribed to each patient will vary. Always follow your physician’s instructions and/or the directions on the prescription drug label. The following dosage information includes the common dose of Ranolazine. If your dose is different, do not follow the dosage described below unless your physician has approved.

The recommended oral dosage of Ranolazine is 500 mg twice a day. This medicine can be taken with or without food. Do not crush, break or chew this medicine. It should be swallowed whole.

What if you miss a dose of Ranolazine?

If your physician has instructed or directed you to take Ranolazine medication in a regular schedule and you have missed a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, instead skip the missed dose and go back to your regular dosing schedule. Do not double the doses unless otherwise directed.

What if you overdose on Ranolazine?

Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately. Some of the overdose symptoms of Ranolazine include fainting, blurred vision, dizziness, vomiting, nausea, tingling, and confusion.

What other drugs could interact with Ranolazine?

It may be noted that drugs other than those listed above may also interact with Ranolazine.

Usually drug interactions occur when it is taken with another drug or with food. Before you take a medication for a particular ailment, you should inform the health expert about intake of any other medications including non-prescription medications, over-the-counter medicines that may increase the effect of Ranolazine, and dietary supplements like vitamins, minerals and herbal, so that the doctor can warn you of any possible drug interactions.

Ranolazine can interact with certain antibiotics, antiarrhythmic medicines, HIV medicines, antidepressants, antipsychotic medicines, heart rhythm medicines, seizure medicines, and barbiturates.

Do let your doctor know if you smoke, consume alcohol or caffeinated drinks, or use illegal drugs as these may interfere with the action of your medication. Make sure to inform your doctor of any medical conditions you may have, or any family history of medical problems. Do not start or stop using any medicine without consulting your doctor.

What are the questions to ask your doctor before taking Ranolazine?

Is it possible for me to take Ranolazine with other drugs?
Should certain beverages, foods and other products be avoided when I take Ranolazine?
What are the possible drug interactions of Ranolazine?
How will Ranolazine work in my body?
How should Ranolazine be taken?
How to reduce the risk of Ranolazine drug interactions and side effects?


The health and medical information provided here is intended to supplement and not substitute for the expertise and judgment of your physician, pharmacists or other health care professional. It should not be understood to indicate that the use of Ranolazine is safe, appropriate or effective for you. Always consult your health care professional before using this, or any other, drug. As Ranolazine may cause dizziness and lightheadedness, caution needs to be exercised while driving car or operating machinery. Do not take Ranolazine if you are taking medications that cause QT prolongation.


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